Detailed information NTG0333717

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK50_RS08890
• Genome accession: NZ_CP042989
• Coordinates: 1971787..1972431 (+)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-010
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966787..1977431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK50_RS08855 (FWK50_08855)	rpmG	1967698..1967868 (-)	171	WP_005542835.1	50S ribosomal protein L33	-
FWK50_RS08860 (FWK50_08860)	rpmB	1967880..1968116 (-)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK50_RS08865 (FWK50_08865)	radC	1968337..1969005 (-)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK50_RS08870 (FWK50_08870)	coaBC	1969178..1970404 (+)	1227	WP_075293534.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK50_RS08875 (FWK50_08875)	dut	1970401..1970856 (+)	456	WP_011608294.1	dUTP diphosphatase	-
FWK50_RS08880 (FWK50_08880)	slmA	1970856..1971515 (+)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK50_RS08885 (FWK50_08885)	-	1971550..1971774 (+)	225	WP_012341336.1	YheU family protein	-
FWK50_RS08890 (FWK50_08890)	crp	1971787..1972431 (+)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK50_RS08895 (FWK50_08895)	recF	1972488..1973564 (-)	1077	WP_075293535.1	DNA replication/repair protein RecF	-
FWK50_RS08900 (FWK50_08900)	dnaN	1973568..1974668 (-)	1101	WP_075293536.1	DNA polymerase III subunit beta	-
FWK50_RS08905 (FWK50_08905)	dnaA	1974680..1976038 (-)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK50_RS08910 (FWK50_08910)	rpmH	1976381..1976515 (+)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK50_RS08915 (FWK50_08915)	rnpA	1976530..1976889 (+)	360	WP_011608287.1	ribonuclease P protein component	-
FWK50_RS08920 (FWK50_08920)	yidD	1976853..1977113 (+)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=333717 FWK50_RS08890 WP_011608291.1 1971787..1972431(+) (crp) [Histophilus somni strain UOC-KLM-ATR-010]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=333717 FWK50_RS08890 WP_011608291.1 1971787..1972431(+) (crp) [Histophilus somni strain UOC-KLM-ATR-010]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAGGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATTTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTAATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411