Detailed information NTG0333661

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK49_RS08920
• Genome accession: NZ_CP042988
• Coordinates: 1971802..1972446 (+)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-09
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966802..1977446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK49_RS08885 (FWK49_08885)	rpmG	1967713..1967883 (-)	171	WP_005542835.1	50S ribosomal protein L33	-
FWK49_RS08890 (FWK49_08890)	rpmB	1967895..1968131 (-)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK49_RS08895 (FWK49_08895)	radC	1968352..1969020 (-)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK49_RS08900 (FWK49_08900)	coaBC	1969193..1970419 (+)	1227	WP_075293534.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK49_RS08905 (FWK49_08905)	dut	1970416..1970871 (+)	456	WP_011608294.1	dUTP diphosphatase	-
FWK49_RS08910 (FWK49_08910)	slmA	1970871..1971530 (+)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK49_RS08915 (FWK49_08915)	-	1971565..1971789 (+)	225	WP_012341336.1	YheU family protein	-
FWK49_RS08920 (FWK49_08920)	crp	1971802..1972446 (+)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK49_RS08925 (FWK49_08925)	recF	1972503..1973579 (-)	1077	WP_075293535.1	DNA replication/repair protein RecF	-
FWK49_RS08930 (FWK49_08930)	dnaN	1973583..1974683 (-)	1101	WP_075293536.1	DNA polymerase III subunit beta	-
FWK49_RS08935 (FWK49_08935)	dnaA	1974695..1976053 (-)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK49_RS08940 (FWK49_08940)	rpmH	1976396..1976530 (+)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK49_RS08945 (FWK49_08945)	rnpA	1976545..1976904 (+)	360	WP_011608287.1	ribonuclease P protein component	-
FWK49_RS08950 (FWK49_08950)	yidD	1976868..1977128 (+)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=333661 FWK49_RS08920 WP_011608291.1 1971802..1972446(+) (crp) [Histophilus somni strain UOC-KLM-ATR-09]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=333661 FWK49_RS08920 WP_011608291.1 1971802..1972446(+) (crp) [Histophilus somni strain UOC-KLM-ATR-09]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAGGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATTTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTAATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411