Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   FWK48_RS00435 Genome accession   NZ_CP042987
Coordinates   88191..90224 (-) Length   677 a.a.
NCBI ID   WP_012341241.1    Uniprot ID   A0A9Q6YZR1
Organism   Histophilus somni strain UOC-KLM-ATR-08     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 83191..95224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FWK48_RS00405 (FWK48_00405) metK 83205..84359 (-) 1155 WP_011609769.1 methionine adenosyltransferase -
  FWK48_RS00410 (FWK48_00410) rppH 84634..85212 (+) 579 WP_011609768.1 RNA pyrophosphohydrolase -
  FWK48_RS00415 (FWK48_00415) - 85223..86017 (+) 795 WP_136121915.1 sulfite exporter TauE/SafE family protein -
  FWK48_RS00420 (FWK48_00420) lgt 86027..86839 (+) 813 WP_075294043.1 prolipoprotein diacylglyceryl transferase -
  FWK48_RS00425 (FWK48_00425) - 86846..87697 (+) 852 WP_075294044.1 thymidylate synthase -
  FWK48_RS00430 (FWK48_00430) tadA 87743..88207 (+) 465 WP_075321230.1 tRNA adenosine(34) deaminase TadA -
  FWK48_RS00435 (FWK48_00435) uvrB 88191..90224 (-) 2034 WP_012341241.1 excinuclease ABC subunit UvrB Machinery gene

Sequence

Protein


Download         Length: 677 a.a.        Molecular weight: 77101.79 Da        Isoelectric Point: 5.2101

>NTDB_id=333557 FWK48_RS00435 WP_012341241.1 88191..90224(-) (uvrB) [Histophilus somni strain UOC-KLM-ATR-08]
MSKINSKPFILHSDFQPAGDQPQAIAKLAENLNDGLAHQTLLGVTGSGKTFTIANVIAKLNRPAMVLAPNKTLAAQLYAE
MKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYLK
MMLHLQHGAIVDQRQILAKLAELQYTRNDQVFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGANFG
AIPRYTIYPKTHYVTPRERILEAIEKIKLELQARREYLLANNRLVEEQRLTQRTQFDIEMMNELGYCSGIENYSRYLSGR
DEGEPPPTLFDYIPSDGLLIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSATP
GPYELEKSGDEIIDQVVRPTGLLDPEVEIRPVAIQVDDLLSEARKRAEQNERVLVTTLTKRMAEDLTDYLEEHGIRVRYL
HSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYADS
ITKSMQKAIDETHRRREKQMKYNAEKGVVPQALNKKVGELLDIGQGAITKSKTKARAKTVAESSALYQKINSPKDYQQQV
KKLEQQMYKFAQDLEFEKAAAIRDQLQELKERFKVGL

Nucleotide


Download         Length: 2034 bp        

>NTDB_id=333557 FWK48_RS00435 WP_012341241.1 88191..90224(-) (uvrB) [Histophilus somni strain UOC-KLM-ATR-08]
ATGAGCAAAATTAACAGTAAGCCTTTTATTTTACATTCCGACTTTCAACCCGCCGGTGATCAGCCACAAGCTATTGCAAA
ATTAGCGGAGAATCTGAATGATGGGTTAGCACATCAAACATTGCTTGGCGTTACCGGATCAGGTAAAACCTTTACGATTG
CCAATGTCATTGCGAAATTGAATCGTCCTGCTATGGTGTTGGCTCCTAATAAAACTTTGGCTGCTCAACTTTATGCGGAA
ATGAAGGCTTTTTTTCCGGAAAATGCGGTGGAATATTTTGTGTCTTATTATGATTATTATCAGCCGGAAGCTTATGTGCC
GAGTAGTGATACGTTTATTGAAAAAGATGCTTCGATTAATGATCAAATTGAGCAAATGCGTTTGTCTGCGACTAAATCTT
TTCTTGAGCGACGAGATACGATTGTAGTCGCTTCTGTTTCTGCGATTTACGGTTTAGGCGATCCGGATAGCTATTTGAAA
ATGATGTTGCATTTGCAACATGGTGCGATTGTTGATCAACGCCAAATTTTGGCGAAATTGGCAGAATTACAATACACCCG
CAATGATCAGGTTTTTCAACGAGGGACATTTAGAGTGCGGGGAGAAATTATTGATATTTTTCCGGCTGAATCTGATGATC
GGGCAGTACGTATTGAGTTATTTGATGATGAAATTGAGCGTTTGAGTTTATTTGATCCACTGACTGGAGCGAATTTTGGT
GCGATACCTCGCTATACTATTTATCCTAAAACGCATTATGTTACACCTCGAGAACGTATTTTAGAGGCGATTGAAAAAAT
TAAGTTGGAACTTCAGGCACGTCGTGAATATTTGTTGGCAAATAATCGCCTTGTAGAGGAACAACGATTAACTCAGCGAA
CTCAATTTGATATTGAGATGATGAATGAGTTGGGATATTGTTCGGGGATTGAAAATTACTCACGTTATTTATCAGGGCGA
GATGAGGGGGAGCCGCCACCAACGTTATTTGATTATATTCCAAGTGACGGTTTGTTAATTATTGATGAAAGCCATGTCAC
TGTTCCGCAAATAGGCGGTATGTATCGTGGCGACCGTTCACGCAAAGAAACGCTTGTGGAATACGGTTTTCGTTTGCCTT
CGGCGTTGGATAATCGCCCATTACGTTTTGAAGAATTTGAGCGTTTAGCACCGCAGACTATCTACGTTTCGGCAACACCG
GGGCCTTATGAATTGGAAAAATCGGGCGATGAAATTATTGATCAGGTTGTGAGACCTACCGGTTTACTCGATCCGGAAGT
GGAGATACGTCCTGTAGCGATTCAAGTTGATGATTTGTTATCGGAAGCAAGGAAAAGAGCGGAGCAAAATGAGCGAGTTT
TGGTCACCACGTTAACCAAACGTATGGCGGAAGATCTCACGGATTATTTGGAAGAACATGGTATTCGGGTTCGCTATTTA
CATTCAGATATTGATACCGTTGAACGTGTTGAAATCATTCGTGATTTGCGTTTAGGTGAATTTGATGTATTAGTTGGGAT
TAACTTACTGCGAGAGGGTTTGGATATTCCGGAAGTTTCCTTAGTTGCGATTTTAGATGCCGATAAAGAGGGGTTTCTTC
GTTCTGAACGTTCTCTTATTCAGACTATCGGTCGTGCGGCACGAAATTTAAACGGAAAAGCGATTTTATACGCAGACAGC
ATAACGAAATCTATGCAAAAAGCGATTGATGAAACTCATCGTCGGCGAGAAAAACAAATGAAATACAATGCGGAAAAAGG
CGTTGTGCCACAGGCTTTAAATAAAAAAGTGGGCGAATTACTGGATATTGGGCAAGGTGCTATAACGAAAAGTAAAACAA
AGGCTCGTGCTAAAACTGTGGCGGAATCGTCCGCACTTTATCAAAAGATAAATTCGCCTAAGGACTATCAACAACAAGTG
AAAAAACTTGAGCAACAGATGTATAAATTTGCCCAAGATTTAGAATTTGAAAAAGCGGCTGCAATTAGAGATCAGTTACA
AGAATTAAAGGAAAGGTTTAAAGTTGGGCTTTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(163-253)

Helicase conserved C-terminal domain (Helicase_C)

(440-548)

UvrB/uvrC motif (UVR)

(638-671)

Ultra-violet resistance protein B (UvrB)

(556-597)

Type III restriction enzyme, res subunit (ResIII)

(17-101)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q6YZR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.887

99.261

0.575
  uvrB Streptococcus pneumoniae R6

57.887

99.261

0.575
  uvrB Streptococcus pneumoniae D39

57.887

99.261

0.575