Detailed information NTG0333391

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: FWK44_RS00770
• Genome accession: NZ_CP042984
• Coordinates: 140424..141068 (-)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain UOC-KLM-ATR-03
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 135424..146068

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK44_RS00740 (FWK44_00740)	yidD	135742..136002 (-)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-
FWK44_RS00745 (FWK44_00745)	rnpA	135966..136325 (-)	360	WP_011608287.1	ribonuclease P protein component	-
FWK44_RS00750 (FWK44_00750)	rpmH	136340..136474 (-)	135	WP_007241546.1	50S ribosomal protein L34	-
FWK44_RS00755 (FWK44_00755)	dnaA	136817..138175 (+)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
FWK44_RS00760 (FWK44_00760)	dnaN	138187..139287 (+)	1101	WP_132994584.1	DNA polymerase III subunit beta	-
FWK44_RS00765 (FWK44_00765)	recF	139291..140367 (+)	1077	WP_132994585.1	DNA replication/repair protein RecF	-
FWK44_RS00770 (FWK44_00770)	crp	140424..141068 (-)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
FWK44_RS00775 (FWK44_00775)	-	141081..141305 (-)	225	WP_012341336.1	YheU family protein	-
FWK44_RS00780 (FWK44_00780)	slmA	141340..141999 (-)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
FWK44_RS00785 (FWK44_00785)	dut	141999..142454 (-)	456	WP_011608294.1	dUTP diphosphatase	-
FWK44_RS00790 (FWK44_00790)	coaBC	142451..143677 (-)	1227	WP_132994586.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
FWK44_RS00795 (FWK44_00795)	radC	143850..144518 (+)	669	WP_011608296.1	DNA repair protein RadC	Machinery gene
FWK44_RS00800 (FWK44_00800)	rpmB	144739..144975 (+)	237	WP_011608297.1	50S ribosomal protein L28	-
FWK44_RS00805 (FWK44_00805)	rpmG	144987..145157 (+)	171	WP_005542835.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=333391 FWK44_RS00770 WP_011608291.1 140424..141068(-) (crp) [Histophilus somni strain UOC-KLM-ATR-03]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=333391 FWK44_RS00770 WP_011608291.1 140424..141068(-) (crp) [Histophilus somni strain UOC-KLM-ATR-03]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAAGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATCTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTGATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411