Detailed information NTG0033334

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SP70585_RS10295
• Genome accession: NC_012468
• Coordinates: 1907108..1908118 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae 70585
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1902108..1913118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS10270 (SP70585_2067)	-	1903319..1903612 (-)	294	WP_000977365.1	hypothetical protein	-
SP70585_RS10275 (SP70585_2068)	-	1903774..1904226 (+)	453	WP_000079148.1	universal stress protein	-
SP70585_RS10280 (SP70585_2069)	-	1904261..1905649 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
SP70585_RS10285 (SP70585_2070)	-	1905715..1906677 (+)	963	WP_001124777.1	asparaginase	-
SP70585_RS10290 (SP70585_2071)	-	1906706..1907044 (-)	339	WP_001092039.1	hypothetical protein	-
SP70585_RS10295 (SP70585_2072)	ccpA	1907108..1908118 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SP70585_RS10300 (SP70585_2073)	-	1908543..1909142 (-)	600	WP_000866724.1	response regulator transcription factor	-
SP70585_RS10305 (SP70585_2074)	-	1909144..1910241 (-)	1098	WP_000893549.1	sensor histidine kinase	-
SP70585_RS10310 (SP70585_2075)	-	1910241..1910978 (-)	738	WP_000832836.1	ABC transporter permease	-
SP70585_RS10315 (SP70585_2076)	-	1910980..1911864 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
SP70585_RS10320 (SP70585_2077)	-	1911851..1912045 (-)	195	WP_000715301.1	hypothetical protein	-
SP70585_RS10325 (SP70585_2078)	-	1912042..1912248 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=33334 SP70585_RS10295 WP_000990607.1 1907108..1908118(-) (ccpA) [Streptococcus pneumoniae 70585]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=33334 SP70585_RS10295 WP_000990607.1 1907108..1908118(-) (ccpA) [Streptococcus pneumoniae 70585]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCTTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568