Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVF73_RS19055 Genome accession   NZ_CP042934
Coordinates   3906683..3907273 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli 042     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3901683..3912273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVF73_RS19040 (FVF73_19045) uhpT 3902323..3903714 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FVF73_RS19045 (FVF73_19050) uhpC 3903852..3905171 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FVF73_RS19050 (FVF73_19055) uhpB 3905181..3906683 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FVF73_RS19055 (FVF73_19060) letA 3906683..3907273 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FVF73_RS19060 (FVF73_19065) ilvN 3907348..3907638 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FVF73_RS19065 (FVF73_19070) ilvB 3907642..3909330 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  FVF73_RS19070 (FVF73_19075) ivbL 3909436..3909534 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  FVF73_RS19080 (FVF73_19085) tisB 3910876..3910965 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FVF73_RS23865 ysdE 3911228..3911302 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=333149 FVF73_RS19055 WP_000633668.1 3906683..3907273(-) (letA) [Escherichia coli 042]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=333149 FVF73_RS19055 WP_000633668.1 3906683..3907273(-) (letA) [Escherichia coli 042]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378