Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SPP_RS10280 Genome accession   NC_012467
Coordinates   1908325..1908627 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae P1031     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1903325..1913627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPP_RS10245 (SPP_2078) rnpA 1904004..1904375 (-) 372 WP_000739246.1 ribonuclease P protein component -
  SPP_RS13780 (SPP_2079) - 1904392..1904523 (-) 132 WP_000768904.1 hypothetical protein -
  SPP_RS10250 (SPP_2080) - 1904524..1905714 (-) 1191 WP_000167766.1 acetate kinase -
  SPP_RS10255 (SPP_2081) comYH 1905765..1906718 (-) 954 WP_000345116.1 class I SAM-dependent methyltransferase Machinery gene
  SPP_RS12415 - 1906779..1907373 (-) 595 Protein_1944 class I SAM-dependent methyltransferase -
  SPP_RS10270 (SPP_2085) comGG/cglG 1907510..1907923 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPP_RS10275 (SPP_2086) comGF/cglF 1907901..1908362 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPP_RS10280 (SPP_2087) comGE/cglE 1908325..1908627 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPP_RS10285 (SPP_2088) comGD/cglD 1908590..1908994 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPP_RS10290 (SPP_2089) comGC/cglC 1908987..1909313 (-) 327 WP_000738633.1 comG operon protein ComGC Machinery gene
  SPP_RS10295 (SPP_2090) comGB/cglB 1909315..1910331 (-) 1017 WP_001844679.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPP_RS10300 (SPP_2091) comGA/cglA/cilD 1910279..1911220 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  SPP_RS10305 (SPP_2092) - 1911296..1911661 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPP_RS10310 (SPP_2093) - 1911812..1912870 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=33263 SPP_RS10280 WP_000413382.1 1908325..1908627(-) (comGE/cglE) [Streptococcus pneumoniae P1031]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=33263 SPP_RS10280 WP_000413382.1 1908325..1908627(-) (comGE/cglE) [Streptococcus pneumoniae P1031]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment