Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   FVP48_RS25435 Genome accession   NZ_CP042892
Coordinates   4787519..4789351 (+) Length   610 a.a.
NCBI ID   WP_118020034.1    Uniprot ID   -
Organism   Escherichia coli O10:H32 strain NMBU-W12E19     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4782519..4794351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVP48_RS25400 (FVP48_26140) dcyD 4782745..4783731 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  FVP48_RS25405 (FVP48_26145) tcyL 4783746..4784414 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FVP48_RS25410 (FVP48_26150) tcyN 4784411..4785163 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FVP48_RS25415 (FVP48_26155) sdiA 4785393..4786115 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  FVP48_RS25420 (FVP48_26160) yecF 4786183..4786407 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FVP48_RS25425 (FVP48_26165) yecU 4786394..4786570 (-) 177 WP_000590344.1 protein YecU -
  FVP48_RS28290 (FVP48_26170) - 4786608..4786724 (-) 117 WP_001302039.1 hypothetical protein -
  FVP48_RS25430 (FVP48_26175) letA 4786866..4787522 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FVP48_RS25435 (FVP48_26180) uvrC 4787519..4789351 (+) 1833 WP_118020034.1 excinuclease ABC subunit UvrC Machinery gene
  FVP48_RS25440 (FVP48_26185) pgsA 4789408..4789956 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FVP48_RS25460 (FVP48_26205) yecA 4790606..4791271 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  FVP48_RS25465 (FVP48_26210) tyrP 4791333..4792544 (-) 1212 WP_000797560.1 tyrosine transporter TyrP -
  FVP48_RS25470 (FVP48_26215) yecH 4792735..4792974 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  FVP48_RS25475 (FVP48_26220) ftnA 4793012..4793509 (-) 498 WP_000917208.1 non-heme ferritin -
  FVP48_RS25480 (FVP48_26225) yecR 4793680..4794003 (-) 324 WP_001237869.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68230.11 Da        Isoelectric Point: 9.3685

>NTDB_id=332608 FVP48_RS25435 WP_118020034.1 4787519..4789351(+) (uvrC) [Escherichia coli O10:H32 strain NMBU-W12E19]
MSDQFDAKAFLKTVTSQPGVYRMYDASGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALISKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=332608 FVP48_RS25435 WP_118020034.1 4787519..4789351(+) (uvrC) [Escherichia coli O10:H32 strain NMBU-W12E19]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTAG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATACCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAATCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGACTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCACCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrB/uvrC motif (UVR)

(205-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374