Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVP48_RS25430 Genome accession   NZ_CP042892
Coordinates   4786866..4787522 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O10:H32 strain NMBU-W12E19     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4781866..4792522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVP48_RS25400 (FVP48_26140) dcyD 4782745..4783731 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  FVP48_RS25405 (FVP48_26145) tcyL 4783746..4784414 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FVP48_RS25410 (FVP48_26150) tcyN 4784411..4785163 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FVP48_RS25415 (FVP48_26155) sdiA 4785393..4786115 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  FVP48_RS25420 (FVP48_26160) yecF 4786183..4786407 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FVP48_RS25425 (FVP48_26165) yecU 4786394..4786570 (-) 177 WP_000590344.1 protein YecU -
  FVP48_RS28290 (FVP48_26170) - 4786608..4786724 (-) 117 WP_001302039.1 hypothetical protein -
  FVP48_RS25430 (FVP48_26175) letA 4786866..4787522 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FVP48_RS25435 (FVP48_26180) uvrC 4787519..4789351 (+) 1833 WP_118020034.1 excinuclease ABC subunit UvrC Machinery gene
  FVP48_RS25440 (FVP48_26185) pgsA 4789408..4789956 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FVP48_RS25460 (FVP48_26205) yecA 4790606..4791271 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=332607 FVP48_RS25430 WP_000611335.1 4786866..4787522(+) (letA) [Escherichia coli O10:H32 strain NMBU-W12E19]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=332607 FVP48_RS25430 WP_000611335.1 4786866..4787522(+) (letA) [Escherichia coli O10:H32 strain NMBU-W12E19]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment