Detailed information NTG0033257

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPP_RS09970
• Genome accession: NC_012467
• Coordinates: 1859035..1860045 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae P1031
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1854035..1865045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPP_RS09945 (SPP_2018)	-	1855245..1855538 (-)	294	WP_000977367.1	hypothetical protein	-
SPP_RS09950 (SPP_2019)	-	1855700..1856152 (+)	453	WP_000079154.1	universal stress protein	-
SPP_RS09955 (SPP_2020)	-	1856187..1857575 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
SPP_RS09960 (SPP_2022)	-	1857641..1858603 (+)	963	WP_001124777.1	asparaginase	-
SPP_RS09965 (SPP_2021)	-	1858600..1858971 (-)	372	WP_001092050.1	hypothetical protein	-
SPP_RS09970 (SPP_2023)	ccpA	1859035..1860045 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SPP_RS09975 (SPP_2024)	-	1860470..1861069 (-)	600	WP_000866726.1	response regulator transcription factor	-
SPP_RS09980 (SPP_2025)	-	1861071..1862168 (-)	1098	WP_000893543.1	sensor histidine kinase	-
SPP_RS09985 (SPP_2026)	-	1862168..1862905 (-)	738	WP_000832838.1	ABC transporter permease	-
SPP_RS09990 (SPP_2027)	-	1862907..1863791 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
SPP_RS09995 (SPP_2028)	-	1863778..1863972 (-)	195	WP_000820179.1	hypothetical protein	-
SPP_RS10000 (SPP_2029)	-	1863969..1864175 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=33257 SPP_RS09970 WP_000990607.1 1859035..1860045(-) (ccpA) [Streptococcus pneumoniae P1031]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=33257 SPP_RS09970 WP_000990607.1 1859035..1860045(-) (ccpA) [Streptococcus pneumoniae P1031]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568