Detailed information NTG0033246

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SPP_RS09340
• Genome accession: NC_012467
• Coordinates: 1755437..1756504 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae P1031
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1750437..1761504

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPP_RS09315 (SPP_1885)	treR	1750623..1751333 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
SPP_RS09320 (SPP_1886)	-	1751366..1752169 (-)	804	WP_000157674.1	ABC transporter ATP-binding protein	-
SPP_RS12850 (SPP_1887)	-	1752182..1753059 (-)	878	Protein_1795	ABC transporter permease	-
SPP_RS09330 (SPP_1889)	-	1753071..1753880 (-)	810	Protein_1796	ABC transporter substrate-binding protein	-
SPP_RS09335 (SPP_1892)	amiF	1754500..1755426 (-)	927	WP_001291296.1	ATP-binding cassette domain-containing protein	Regulator
SPP_RS09340 (SPP_1893)	amiE	1755437..1756504 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
SPP_RS09345 (SPP_1894)	amiD	1756513..1757439 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
SPP_RS09350 (SPP_1895)	amiC	1757439..1758935 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
SPP_RS09355 (SPP_1896)	amiA3	1759002..1760981 (-)	1980	WP_000742231.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=33246 SPP_RS09340 WP_000159554.1 1755437..1756504(-) (amiE) [Streptococcus pneumoniae P1031]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=33246 SPP_RS09340 WP_000159554.1 1755437..1756504(-) (amiE) [Streptococcus pneumoniae P1031]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541