Detailed information NTG0033245

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HICON_RS01370
• Genome accession: NC_014922
• Coordinates: 297226..299796 (-)
• Length: 856 a.a.
• NCBI ID: WP_013527305.1
• Uniprot ID: -
• Organism: Haemophilus influenzae F3047
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 292226..304796

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HICON_RS01355 (HICON_05420)	-	293567..293848 (-)	282	WP_013526240.1	virulence factor	-
HICON_RS01360 (HICON_05430)	rnr	294044..296392 (+)	2349	WP_013526241.1	ribonuclease R	-
HICON_RS01365 (HICON_05440)	rlmB	296448..297188 (+)	741	WP_013527304.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
HICON_RS01370 (HICON_05450)	clpC	297226..299796 (-)	2571	WP_013527305.1	ATP-dependent chaperone ClpB	Regulator
HICON_RS01375 (HICON_05460)	-	299924..300487 (-)	564	WP_013527306.1	5-formyltetrahydrofolate cyclo-ligase	-
HICON_RS01380 (HICON_05470)	-	300786..301088 (-)	303	WP_005651366.1	cell division protein ZapA	-
HICON_RS01385 (HICON_05480)	polA	301237..304029 (+)	2793	WP_041175141.1	DNA polymerase I	-
HICON_RS01390 (HICON_05490)	-	304044..304391 (+)	348	WP_006995516.1	hypothetical protein	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95765.16 Da
• Isoelectric Point: 5.0182

>NTDB_id=33245 HICON_RS01370 WP_013527305.1 297226..299796(-) (clpC) [Haemophilus influenzae F3047]
MNIEKFTTKFQEALSEAQSLAIGKDNQFIEPVHLLTALLNQQGGSIAPILTASGVNVALLRNELKTELNKLPQVIGNGGD
VQLSRQLINLLNLCDKFAQQNQDKFISSELFLLAALEERGTISDILKKCGAKKEQISQAIQHIRGGQNVNDQNAEESRQA
LEKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVDEPSVEDTIAILRGLKERYEIHHHVDITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPEPLDRLERRIIQLKLEQQALQKEEDEASRKRLEMLEKELAEKEREYAELEEVWKSEKATLSGSQHIKQELD
TAKTELEQARRAGDLAKMSELQYGRIPALEKQLEQAETSEGKEMTLLRYRVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEEELHKRVIGQNEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLAKFLFDSEDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHADVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQGNKDESYSEMKALVMSVVSQHFRPEFINRIDETVVFHPLGKENIRAIASIQLERLAKRMETRGYELVFTDDLLD
FIGEVGYDPIYGARPLKRAIQQEIENSLAQQILSGALLPGKFVTIDYANAEVQARQ

Nucleotide

• Length: 2571 bp

>NTDB_id=33245 HICON_RS01370 WP_013527305.1 297226..299796(-) (clpC) [Haemophilus influenzae F3047]
ATGAACATTGAAAAATTTACAACAAAGTTCCAAGAAGCGTTAAGCGAAGCACAATCACTTGCTATCGGAAAAGACAATCA
ATTTATTGAACCTGTGCATTTATTGACCGCACTTTTAAATCAACAGGGCGGCTCTATTGCGCCAATTTTGACAGCAAGTG
GTGTAAATGTGGCGTTATTGCGTAATGAATTAAAGACAGAACTAAATAAATTGCCGCAAGTGATTGGCAATGGTGGAGAT
GTACAACTTTCACGCCAGCTTATTAATCTACTTAATTTATGCGATAAATTTGCACAGCAAAACCAAGATAAATTTATTTC
GAGCGAATTGTTTTTGCTTGCAGCTTTAGAAGAACGAGGAACGATCAGCGATATTTTGAAAAAGTGCGGTGCGAAAAAAG
AACAAATTTCTCAAGCTATTCAGCACATTAGAGGGGGACAAAACGTGAACGATCAAAATGCAGAAGAAAGCAGACAAGCT
CTTGAAAAATATACGATTGATTTAACTGCTCGTGCAGAAAGTGGCAAACTTGATCCTGTAATTGGGCGTGATGAAGAAAT
TCGTCGAGCCATTCAAGTATTACAACGTCGTACTAAAAACAACCCTGTGTTAATTGGTGAACCAGGTGTAGGGAAAACGG
CGATTGTCGAAGGCTTGGCACAGCGCATCGTAAACGGCGAAGTGCCAGAAGGTTTGAAAAATAAACGTGTGCTTTCATTA
GATATGGGCGCATTGATTGCTGGTGCAAAATATCGCGGAGAATTTGAAGAACGTTTAAAAGCGGTGCTCAATGAACTTTC
GAAAGAAGAAGGTCGCGTGATCCTCTTTATTGACGAAATTCATACTATGGTCGGCGCGGGTAAAACAGATGGTGCAATGG
ACGCGGGTAACTTATTAAAACCAAGTTTGGCACGAGGCGAATTACATTGCGTGGGTGCAACCACTTTAGATGAATATCGT
CAATATATCGAAAAAGATGCCGCACTTGAGCGTCGTTTCCAAAAAGTCTTTGTGGACGAACCTAGTGTAGAAGATACCAT
TGCGATCTTACGTGGTTTGAAAGAACGCTATGAAATTCATCATCACGTAGATATTACTGACCCAGCAATCGTAGCAGCGG
CAACGCTTTCACACCGTTATATTTCCGATCGTCAGTTACCAGATAAAGCCATTGATTTGATCGATGAAGCAGCGTCTAGC
ATTCGTATGGAAATAGATTCTAAACCTGAACCGCTTGATCGTCTTGAACGTCGAATTATCCAACTAAAATTGGAACAACA
GGCATTACAAAAAGAAGAAGACGAAGCAAGTCGCAAACGTTTAGAAATGTTAGAGAAAGAATTAGCTGAAAAAGAACGTG
AATATGCCGAACTTGAAGAAGTGTGGAAATCTGAAAAAGCAACGCTTTCTGGCTCTCAACATATTAAACAAGAGTTAGAT
ACTGCAAAAACCGAACTAGAACAAGCTCGTCGCGCGGGTGATTTAGCGAAAATGTCAGAGTTGCAATATGGCCGCATCCC
TGCTCTTGAAAAGCAACTTGAGCAAGCTGAAACCAGCGAAGGAAAAGAAATGACGCTTTTGCGCTATCGCGTCACAGATG
AAGAAATTGCAGAAGTGCTTTCTAAAGCTACAGGCATCCCTGTATCCAAAATGATGGAAGGCGAGAAAGAAAAACTCTTG
CGTATGGAAGAAGAATTGCATAAACGTGTTATCGGACAAAACGAAGCCGTGGATGCGGTAGCAAACGCGATTCGTCGTAG
TCGTGCTGGTCTTTCCGATCCTAATCGCCCAATTGGTTCTTTCTTATTCCTAGGGCCAACAGGTGTAGGTAAAACAGAGC
TTTGTAAAACTTTGGCTAAATTCTTGTTTGATAGTGAAGATGCGATGGTGCGCATTGATATGTCAGAGTTTATGGAAAAA
CACAGCGTCTCTCGTTTAGTGGGTGCCCCTCCAGGCTATGTCGGCTATGAAGAAGGCGGTTATTTAACTGAAGCTGTTCG
TCGTCGTCCGTATTCAGTGATTTTGCTCGATGAAGTTGAAAAAGCCCATGCGGATGTATTCAACATTTTATTACAAGTGT
TGGATGATGGTCGTTTAACTGACGGACAAGGTCGTACTGTGGACTTCCGTAACACTGTGGTGATTATGACCTCTAACTTG
GGTTCTGATTTAATCCAAGGTAATAAAGACGAAAGCTATAGCGAAATGAAAGCCTTAGTGATGTCAGTGGTTAGCCAACA
TTTCCGTCCCGAATTCATCAACCGTATTGACGAAACGGTGGTATTCCATCCACTTGGTAAAGAAAATATCCGTGCGATTG
CAAGTATCCAATTAGAACGCTTAGCAAAACGTATGGAAACTCGTGGCTATGAATTAGTGTTTACCGACGATTTATTAGAT
TTCATTGGTGAAGTGGGTTACGACCCAATTTATGGCGCGCGTCCATTAAAACGTGCAATTCAACAAGAGATCGAAAACAG
CTTGGCACAACAAATTCTATCTGGTGCGTTATTACCTGGTAAGTTTGTTACCATTGATTATGCCAACGCAGAAGTTCAAG
CGAGACAATAG

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (765-844)

• AAA lid domain (AAA_lid_9) (342-443)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.066	100	0.478
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.458	100	0.446
clpE	Streptococcus pneumoniae TIGR4	49.267	79.673	0.393
clpE	Streptococcus pneumoniae R6	48.458	79.556	0.386
clpE	Streptococcus pneumoniae Rx1	48.458	79.556	0.386
clpE	Streptococcus pneumoniae D39	48.458	79.556	0.386
clpE	Streptococcus mutans UA159	47.577	79.556	0.379
clpC	Lactococcus lactis subsp. cremoris KW2	45.184	82.477	0.373