Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVE20_RS22100 Genome accession   NZ_CP042846
Coordinates   4551869..4552459 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain JME64     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4546869..4557459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE20_RS22085 uhpT 4547509..4548900 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FVE20_RS22090 uhpC 4549038..4550357 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FVE20_RS22095 uhpB 4550367..4551869 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FVE20_RS22100 letA 4551869..4552459 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FVE20_RS22105 ilvN 4552535..4552825 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FVE20_RS22110 ilvB 4552829..4554517 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  FVE20_RS22115 ivbL 4554623..4554721 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  FVE20_RS22120 tisB 4555286..4555375 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  FVE20_RS22780 ysdE 4555499..4555573 (-) 75 WP_211180519.1 protein YsdE -
  FVE20_RS22125 emrD 4555655..4556839 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FVE20_RS22130 yidF 4556847..4557344 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=332281 FVE20_RS22100 WP_000633668.1 4551869..4552459(-) (letA) [Escherichia coli strain JME64]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=332281 FVE20_RS22100 WP_000633668.1 4551869..4552459(-) (letA) [Escherichia coli strain JME64]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378