Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FVE20_RS20465 Genome accession   NZ_CP042846
Coordinates   4187852..4188484 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain JME64     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4182852..4193484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE20_RS20440 yheS 4183021..4184934 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  FVE20_RS20445 yheT 4184934..4185956 (+) 1023 WP_000057356.1 hydrolase -
  FVE20_RS20450 yheU 4185950..4186168 (+) 219 WP_000907085.1 YheU family protein -
  FVE20_RS20455 prkB 4186222..4187091 (+) 870 WP_001274680.1 phosphoribulokinase -
  FVE20_RS20460 yhfA 4187146..4187550 (-) 405 WP_001148908.1 OsmC family protein -
  FVE20_RS20465 crp 4187852..4188484 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FVE20_RS20470 yhfK 4188535..4190625 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  FVE20_RS20475 argD 4190692..4191912 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FVE20_RS20480 pabA 4191998..4192561 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  FVE20_RS20485 fic 4192593..4193195 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  FVE20_RS20490 yhfG 4193185..4193352 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=332273 FVE20_RS20465 WP_000242755.1 4187852..4188484(+) (crp) [Escherichia coli strain JME64]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=332273 FVE20_RS20465 WP_000242755.1 4187852..4188484(+) (crp) [Escherichia coli strain JME64]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment