Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FVE21_RS20475 Genome accession   NZ_CP042845
Coordinates   4189598..4190230 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain JME65     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4184598..4195230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE21_RS20450 yheS 4184767..4186680 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  FVE21_RS20455 yheT 4186680..4187702 (+) 1023 WP_000057356.1 hydrolase -
  FVE21_RS20460 yheU 4187696..4187914 (+) 219 WP_000907085.1 YheU family protein -
  FVE21_RS20465 prkB 4187968..4188837 (+) 870 WP_001274680.1 phosphoribulokinase -
  FVE21_RS20470 yhfA 4188892..4189296 (-) 405 WP_001148908.1 OsmC family protein -
  FVE21_RS20475 crp 4189598..4190230 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FVE21_RS20480 yhfK 4190281..4192371 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  FVE21_RS20485 argD 4192438..4193658 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FVE21_RS20490 pabA 4193744..4194307 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  FVE21_RS20495 fic 4194339..4194941 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  FVE21_RS20500 yhfG 4194931..4195098 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=332191 FVE21_RS20475 WP_000242755.1 4189598..4190230(+) (crp) [Escherichia coli strain JME65]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=332191 FVE21_RS20475 WP_000242755.1 4189598..4190230(+) (crp) [Escherichia coli strain JME65]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467