Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVE22_RS22130 Genome accession   NZ_CP042844
Coordinates   4556982..4557572 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain JME66     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4551982..4562572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE22_RS22115 uhpT 4552622..4554013 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FVE22_RS22120 uhpC 4554151..4555470 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FVE22_RS22125 uhpB 4555480..4556982 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FVE22_RS22130 letA 4556982..4557572 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FVE22_RS22135 ilvN 4557648..4557938 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FVE22_RS22140 ilvB 4557942..4559630 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  FVE22_RS22145 ivbL 4559736..4559834 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  FVE22_RS22150 tisB 4560399..4560488 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  FVE22_RS22810 ysdE 4560612..4560686 (-) 75 WP_211180519.1 protein YsdE -
  FVE22_RS22155 emrD 4560768..4561952 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FVE22_RS22160 yidF 4561960..4562457 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=332117 FVE22_RS22130 WP_000633668.1 4556982..4557572(-) (letA) [Escherichia coli strain JME66]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=332117 FVE22_RS22130 WP_000633668.1 4556982..4557572(-) (letA) [Escherichia coli strain JME66]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378