Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FGL73_RS08565 Genome accession   NZ_CP042408
Coordinates   1781006..1782976 (-) Length   656 a.a.
NCBI ID   WP_146978291.1    Uniprot ID   -
Organism   Lactococcus lactis strain CBA3619     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1776006..1787976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL73_RS08525 (FGL73_08525) - 1776197..1776499 (+) 303 Protein_1690 integrase core domain-containing protein -
  FGL73_RS08530 (FGL73_08530) - 1776743..1777027 (-) 285 WP_038602483.1 bacteriocin immunity protein -
  FGL73_RS08535 (FGL73_08535) - 1777065..1777238 (-) 174 WP_229049640.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  FGL73_RS08540 (FGL73_08540) - 1777350..1777670 (-) 321 WP_038602485.1 hypothetical protein -
  FGL73_RS08545 (FGL73_08545) - 1777805..1777966 (-) 162 WP_118263635.1 bacteriocin -
  FGL73_RS08550 (FGL73_08550) - 1778152..1779036 (-) 885 WP_038602487.1 XRE/MutR family transcriptional regulator -
  FGL73_RS08555 (FGL73_08555) ruvB 1779173..1780174 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  FGL73_RS08560 (FGL73_08560) ruvA 1780301..1780894 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  FGL73_RS08565 (FGL73_08565) hexB 1781006..1782976 (-) 1971 WP_146978291.1 DNA mismatch repair endonuclease MutL Machinery gene
  FGL73_RS08570 (FGL73_08570) - 1783105..1783800 (-) 696 WP_146978292.1 hypothetical protein -
  FGL73_RS08575 (FGL73_08575) hexA 1783915..1786437 (-) 2523 WP_038602495.1 DNA mismatch repair protein MutS Machinery gene
  FGL73_RS08580 (FGL73_08580) - 1786630..1786977 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -
  FGL73_RS08590 (FGL73_08590) - 1787318..1787626 (-) 309 WP_047207033.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73734.12 Da        Isoelectric Point: 5.3227

>NTDB_id=331618 FGL73_RS08565 WP_146978291.1 1781006..1782976(-) (hexB) [Lactococcus lactis strain CBA3619]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLVAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSLP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKEILSVQTELPLQNNPLYYDNIRQDFYVREEATFKINKNQASNDSTEQTFDNFTE
NQLNTDAVSEKMIDRTVESTTEITDKSLENTVSNFGIDFDNEVKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFVVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=331618 FGL73_RS08565 WP_146978291.1 1781006..1782976(-) (hexB) [Lactococcus lactis strain CBA3619]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAGTTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GGATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGCTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCTTACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCAATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCATTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GATTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATATTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGACTGAACAAACTTTTGATAATTTTACAGAA
AATCAGCTCAATACTGATGCTGTCAGTGAAAAAATGATTGACAGAACTGTTGAAAGTACTACTGAAATTACTGACAAGAG
TCTAGAAAATACTGTCAGCAACTTTGGAATTGATTTTGATAATGAAGTAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATTAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTAGCCAAAAATGATTTTGTTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACGGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGACGCCGAGTCAGCTAGAGCTTTACTCGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(455-598)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

57.362

99.39

0.57