Detailed information NTG0331619

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FGL73_RS08575
• Genome accession: NZ_CP042408
• Coordinates: 1783915..1786437 (-)
• Length: 840 a.a.
• NCBI ID: WP_038602495.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain CBA3619
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1778915..1791437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL73_RS08555 (FGL73_08555)	ruvB	1779173..1780174 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
FGL73_RS08560 (FGL73_08560)	ruvA	1780301..1780894 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
FGL73_RS08565 (FGL73_08565)	hexB	1781006..1782976 (-)	1971	WP_146978291.1	DNA mismatch repair endonuclease MutL	Machinery gene
FGL73_RS08570 (FGL73_08570)	-	1783105..1783800 (-)	696	WP_146978292.1	hypothetical protein	-
FGL73_RS08575 (FGL73_08575)	hexA	1783915..1786437 (-)	2523	WP_038602495.1	DNA mismatch repair protein MutS	Machinery gene
FGL73_RS08580 (FGL73_08580)	-	1786630..1786977 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
FGL73_RS08590 (FGL73_08590)	-	1787318..1787626 (-)	309	WP_047207033.1	helix-turn-helix domain-containing protein	-
FGL73_RS08595 (FGL73_08595)	-	1787756..1788070 (+)	315	WP_098394237.1	hypothetical protein	-
FGL73_RS08600 (FGL73_08600)	-	1788082..1788492 (+)	411	WP_146978293.1	DUF6591 domain-containing protein	-
FGL73_RS08605 (FGL73_08605)	-	1788536..1789417 (-)	882	WP_058206124.1	NAD(P)-dependent oxidoreductase	-
FGL73_RS12610	-	1789459..1789665 (-)	207	WP_003132002.1	hypothetical protein	-
FGL73_RS08620 (FGL73_08620)	-	1789897..1790274 (-)	378	WP_058206123.1	DUF1634 domain-containing protein	-
FGL73_RS08625 (FGL73_08625)	-	1790274..1791125 (-)	852	WP_038602517.1	sulfite exporter TauE/SafE family protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94163.09 Da
• Isoelectric Point: 4.6772

>NTDB_id=331619 FGL73_RS08575 WP_038602495.1 1783915..1786437(-) (hexA) [Lactococcus lactis strain CBA3619]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQLEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEDLRSQLDELPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKAIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFAENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=331619 FGL73_RS08575 WP_038602495.1 1783915..1786437(-) (hexA) [Lactococcus lactis strain CBA3619]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCTCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTCAAACGGGCAGTGACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCTTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTA
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAACTTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCTTTAG
AAAATCAGGTCGCTTCAAAATTGTTGGCTTACGTAAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAAACGAAAACAGCGATGGGAACCCGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCTGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTGTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAACTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAACGAAGCTC
CGTTAGAAGATTTAAGAAGCCAATTAGACGAGCTTCCGGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGAACTTCTTGGATTGCAAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTAAGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAGGCGCGTGAAAAATCATCTTC
TCTAGAATATGATTTATTCATGGGACTTCGGACTGAAACTGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAGCAA
TTGCTGAAATTGACTGTTTACAAAGTTTATCTGTCGTTGCCGAAAAACAAGGTTATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCAAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACTTTGGAACAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGGCCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTGCTGAAAACTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (124-237)

• MutS domain V (MutS_V) (598-784)

• MutS domain III (MutS_III) (254-544)

• MutS domain I (MutS_I) (7-116)

• MutS family domain IV (MutS_IV) (413-503)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.455	100	0.648
mutS	Pseudomonas stutzeri strain ATCC 17587	37.923	100	0.387