Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FS836_RS18930 Genome accession   NZ_CP042352
Coordinates   3855975..3856565 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM9513     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3850975..3861565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FS836_RS18915 (FS836_19015) uhpT 3851615..3853006 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FS836_RS18920 (FS836_19020) uhpC 3853144..3854463 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FS836_RS18925 (FS836_19025) uhpB 3854473..3855975 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FS836_RS18930 (FS836_19030) letA 3855975..3856565 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FS836_RS18935 (FS836_19035) ilvN 3856640..3856930 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FS836_RS18940 (FS836_19040) ilvB 3856934..3858622 (-) 1689 WP_061348785.1 acetolactate synthase large subunit -
  FS836_RS18945 (FS836_19045) ivbL 3858728..3858826 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  FS836_RS18950 (FS836_19050) tisB 3859391..3859480 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FS836_RS18955 ysdE 3859604..3859678 (-) 75 WP_211180519.1 protein YsdE -
  FS836_RS18960 (FS836_19055) emrD 3859760..3860944 (+) 1185 WP_123297862.1 multidrug efflux MFS transporter EmrD -
  FS836_RS18965 (FS836_19060) yidF 3860952..3861449 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=331471 FS836_RS18930 WP_000633668.1 3855975..3856565(-) (letA) [Escherichia coli strain RM9513]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=331471 FS836_RS18930 WP_000633668.1 3855975..3856565(-) (letA) [Escherichia coli strain RM9513]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378