Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FS611_RS21785 Genome accession   NZ_CP042350
Coordinates   4326438..4327028 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM10410     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4321438..4332028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FS611_RS21770 (FS611_21765) uhpT 4322078..4323469 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FS611_RS21775 (FS611_21770) uhpC 4323607..4324926 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FS611_RS21780 (FS611_21775) uhpB 4324936..4326438 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FS611_RS21785 (FS611_21780) letA 4326438..4327028 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FS611_RS21790 (FS611_21785) ilvN 4327104..4327394 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FS611_RS21795 (FS611_21790) ilvB 4327398..4329086 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  FS611_RS21800 (FS611_21795) ivbL 4329192..4329290 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  FS611_RS21805 (FS611_21800) tisB 4329854..4329943 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  FS611_RS26550 ysdE 4330067..4330141 (-) 75 WP_211180519.1 protein YsdE -
  FS611_RS21810 (FS611_21805) emrD 4330223..4331407 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FS611_RS21815 (FS611_21810) yidF 4331415..4331912 (-) 498 WP_040077900.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=331387 FS611_RS21785 WP_000633668.1 4326438..4327028(-) (letA) [Escherichia coli strain RM10410]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=331387 FS611_RS21785 WP_000633668.1 4326438..4327028(-) (letA) [Escherichia coli strain RM10410]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378