Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EJF26_RS07085 Genome accession   NZ_CP034442
Coordinates   1415315..1416613 (-) Length   432 a.a.
NCBI ID   WP_000867716.1    Uniprot ID   F9P287
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1410315..1421613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS07065 - 1410636..1412609 (-) 1974 WP_000739993.1 DHH family phosphoesterase -
  EJF26_RS07070 - 1412762..1413940 (-) 1179 WP_000656058.1 acetyl-CoA C-acetyltransferase -
  EJF26_RS07075 hpf 1414028..1414576 (-) 549 WP_000599119.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EJF26_RS07080 comFC/cflB 1414656..1415318 (-) 663 WP_000995710.1 ComF family protein Machinery gene
  EJF26_RS07085 comFA/cflA 1415315..1416613 (-) 1299 WP_000867716.1 DEAD/DEAH box helicase Machinery gene
  EJF26_RS07090 - 1416671..1417306 (+) 636 WP_000395764.1 YigZ family protein -
  EJF26_RS07095 cysK 1417462..1418388 (+) 927 WP_001029449.1 cysteine synthase A -
  EJF26_RS07100 tsf 1418503..1419543 (-) 1041 WP_000808061.1 translation elongation factor Ts -
  EJF26_RS07105 rpsB 1419622..1420401 (-) 780 WP_000268474.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49688.71 Da        Isoelectric Point: 9.0394

>NTDB_id=331367 EJF26_RS07085 WP_000867716.1 1415315..1416613(-) (comFA/cflA) [Streptococcus oralis subsp. dentisani strain F0392]
MKVNPNYLGRLFTEKELTKEERQMAVKLPAMRKEKGKLFCQRCNSTILEEWYLPIDAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLIRAVERREPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACEIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNSMLYYAVKNGVKEDGLRIFLTATST
DELDKKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRYLDKSQLSPKLKTSIEKQRRTGYPLLIFASEIKKGEKLKEI
LQEQFSKENIGFVSSVTEDRLEQVQAFRDGKLTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNTSIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=331367 EJF26_RS07085 WP_000867716.1 1415315..1416613(-) (comFA/cflA) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAAGTAAATCCAAATTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTAAAGAAGAACGTCAGATGGCCGTGAA
ACTGCCAGCAATGAGAAAAGAGAAGGGAAAACTTTTCTGTCAACGTTGTAATAGTACGATTCTAGAAGAATGGTATTTGC
CTATTGACGCTTACTATTGTAGGGAGTGCTTGCTGATGAAGCGAGTTAGGAGTGATCAAGCTTTATACTATTTTCCACAG
GAGGATTTTCCGAAACAAGATGTTCTCAAATGGCGTGGCCAATTGACTCCTTTTCAAGAGAAGGTGTCAGAGGGATTGAT
TCGAGCAGTTGAAAGGAGAGAACCTACCTTAGTTCATGCTGTCACAGGAGCTGGAAAGACAGAGATGATTTATCAAGTTG
TAGCCAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATCGATGTATGTTTGGAATTGTATAAGCGA
CTGCAGAATGACTTTGCTTGTGAGATAGCACTACTTCATGGTGAATCAGAGCCCTATTTTCGAACTCCACTAGTTGTTGC
AACGACGCATCAGTTATTAAAATTTTATCATGCCTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAATTCTATGCTTTACTATGCTGTAAAGAATGGTGTAAAGGAGGATGGGTTAAGGATATTCCTTACAGCGACTTCTACA
GATGAGTTAGATAAGAAGGTTCGCACAGGAGAATTAAAACGATTGAGCTTGCCAAGACGATTTCATGGAAATCCATTGAT
TATTCCAAAGCCAGTTTGGTTATCGGATTTTAATCGTTACTTAGATAAGAGTCAGTTGTCACCCAAATTAAAGACCTCCA
TTGAGAAGCAGAGAAGAACAGGTTATCCATTGTTAATCTTTGCATCAGAAATTAAAAAAGGCGAGAAACTAAAAGAAATA
TTGCAGGAACAGTTTTCAAAAGAAAATATCGGCTTTGTGTCTTCTGTGACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAAAGCTAACAATACTGATCAGTACGACAATCTTGGAACGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGCTTGATTCAGATTGGTGGGCGAGTTGGGCGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATACTTCCATCAAAAAGGCAATCAAGGAAATCAAGCAGATGAA
TAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P287

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.046

100

0.9
  comFA/cflA Streptococcus mitis SK321

90.046

100

0.9
  comFA/cflA Streptococcus pneumoniae Rx1

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae D39

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae R6

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae TIGR4

89.583

100

0.896
  comFA Lactococcus lactis subsp. cremoris KW2

51.589

94.676

0.488
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

99.769

0.377

Multiple sequence alignment