Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FRV13_RS17925 Genome accession   NZ_CP042298
Coordinates   3207871..3208461 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM9088     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3202871..3213461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FRV13_RS17895 (FRV13_17900) yidF 3202988..3203485 (+) 498 WP_000148063.1 radical SAM protein -
  FRV13_RS17900 (FRV13_17905) emrD 3203493..3204677 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FRV13_RS28530 ysdE 3204759..3204833 (+) 75 WP_211180519.1 protein YsdE -
  FRV13_RS17905 (FRV13_17910) tisB 3204957..3205046 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FRV13_RS17910 (FRV13_17915) ivbL 3205611..3205709 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  FRV13_RS17915 (FRV13_17920) ilvB 3205815..3207503 (+) 1689 WP_000168464.1 acetolactate synthase large subunit -
  FRV13_RS17920 (FRV13_17925) ilvN 3207507..3207797 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FRV13_RS17925 (FRV13_17930) letA 3207871..3208461 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FRV13_RS17930 (FRV13_17935) uhpB 3208461..3209963 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FRV13_RS17935 (FRV13_17940) uhpC 3209973..3211292 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FRV13_RS17940 (FRV13_17945) uhpT 3211430..3212821 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=330949 FRV13_RS17925 WP_000633668.1 3207871..3208461(+) (letA) [Escherichia coli strain RM9088]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=330949 FRV13_RS17925 WP_000633668.1 3207871..3208461(+) (letA) [Escherichia coli strain RM9088]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378