Detailed information NTG0330907

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EIP87_RS08795
• Genome accession: NZ_CP034354
• Coordinates: 1812317..1813654 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain IMP-13
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1807317..1818654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EIP87_RS08770 (EIP87_08770)	pgeF	1807460..1808188 (-)	729	WP_043096283.1	peptidoglycan editing factor PgeF	-
EIP87_RS08775 (EIP87_08775)	rluD	1808185..1809147 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EIP87_RS08780 (EIP87_08780)	-	1809293..1810318 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EIP87_RS08785 (EIP87_08785)	-	1810475..1810720 (+)	246	WP_003102591.1	PP0621 family protein	-
EIP87_RS08790 (EIP87_08790)	pilS	1810710..1812302 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
EIP87_RS08795 (EIP87_08795)	pilR	1812317..1813654 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EIP87_RS08800 (EIP87_08800)	thiO	1813700..1814794 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
EIP87_RS08805 (EIP87_08805)	-	1814929..1815438 (+)	510	WP_043096282.1	Tfp pilus assembly protein FimT/FimU	-
EIP87_RS08810 (EIP87_08810)	-	1815544..1816050 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
EIP87_RS08815 (EIP87_08815)	pilV	1816041..1816598 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EIP87_RS08820 (EIP87_08820)	pilW	1816595..1817419 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EIP87_RS08825 (EIP87_08825)	pilX	1817416..1818003 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=330907 EIP87_RS08795 WP_003094694.1 1812317..1813654(+) (pilR) [Pseudomonas aeruginosa strain IMP-13]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=330907 EIP87_RS08795 WP_003094694.1 1812317..1813654(+) (pilR) [Pseudomonas aeruginosa strain IMP-13]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384