Detailed information NTG0033038

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: BAMF_RS40080
• Genome accession: NC_014551
• Coordinates: 3916097..3917293 (-)
• Length: 398 a.a.
• NCBI ID: WP_013354214.1
• Uniprot ID: A0A9P1NK46
• Organism: Bacillus amyloliquefaciens DSM 7 = ATCC 23350
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3911097..3922293

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BAMF_RS41625 (BAMF_3850)	-	3912059..3912322 (-)	264	WP_013354210.1	hypothetical protein	-
BAMF_RS40065 (BAMF_3851)	-	3912501..3913919 (-)	1419	WP_013354211.1	sensor histidine kinase	-
BAMF_RS40070 (BAMF_3852)	-	3913916..3914599 (-)	684	WP_013354212.1	response regulator transcription factor	-
BAMF_RS40075 (BAMF_3853)	-	3914813..3915724 (+)	912	WP_013354213.1	PepSY domain-containing protein	-
BAMF_RS40080 (BAMF_3854)	htrA	3916097..3917293 (-)	1197	WP_013354214.1	S1C family serine protease	Regulator
BAMF_RS40085 (BAMF_3855)	vicX	3917380..3918174 (-)	795	WP_013354215.1	MBL fold metallo-hydrolase	Regulator
BAMF_RS40090 (BAMF_3856)	-	3918190..3919029 (-)	840	WP_013354216.1	two-component system regulatory protein YycI	-
BAMF_RS40095 (BAMF_3857)	yycH	3919016..3920374 (-)	1359	WP_013354217.1	two-component system activity regulator YycH	-
BAMF_RS40100 (BAMF_3858)	walK	3920364..3922199 (-)	1836	WP_013354218.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42734.68 Da
• Isoelectric Point: 7.4579

>NTDB_id=33038 BAMF_RS40080 WP_013354214.1 3916097..3917293(-) (htrA) [Bacillus amyloliquefaciens DSM 7 = ATCC 23350]
MDYNRDDEQYAPEQPRRSKRGYFLSSLIGVIVGAALMGLLLPYWTGGDHGESSKSANQRIGSEQVKTVNVNINDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDDSRVPAELIGSDRLMDLAV
LKVKTDKIKSVAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDIVDLRERLYRKKIGDRVKITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=33038 BAMF_RS40080 WP_013354214.1 3916097..3917293(-) (htrA) [Bacillus amyloliquefaciens DSM 7 = ATCC 23350]
GTGGATTATAATCGCGATGATGAACAGTACGCCCCCGAGCAGCCCCGCCGCAGCAAGAGAGGATACTTCCTTTCAAGTCT
GATCGGTGTCATCGTCGGGGCCGCGCTCATGGGTTTACTGCTGCCGTACTGGACAGGCGGAGACCATGGAGAAAGCAGCA
AAAGCGCCAATCAGCGCATCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATATCAATGATGCTGTCACGAATATGGTC
AGCCGTGTATCGGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCCGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AAATTGAGATCAGCCTGAAAGATGACTCGCGCGTGCCTGCCGAGCTGATCGGGAGCGACCGTCTGATGGATCTTGCCGTG
TTGAAGGTGAAGACTGATAAAATCAAATCGGTCGCCCAATTCGGCAATTCTGATCAAGTGAAAGTTGGCGAGCCGGTCAT
TGCGATCGGAAACCCGCTCGGACTTGAATTTGCGGGATCGGTGACACAAGGGATCATTTCAGGAACGGAAAGGGCGGTTC
CCGTTGACTCAAACGGCGACGGACAGCCTGATTGGAATGCGGAAGTGCTGCAGACCGACGCCGCGATTAATCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATTGCTGAATCCGCCGTTGAAGG
AATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCTTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTCAAACTTCCGAAGGGTGTT
AAAACCGGAGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCTGGAAAAGCAGGCTTGAAAAAGCTCGACGTGATCAC
CGGATTCGACGGACATAAGGTCAATGACATTGTCGATCTCCGTGAGCGTCTGTATCGCAAAAAGATCGGCGACCGTGTCA
AGATCACGTTCTACCGTTCAGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTGCAGAAATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• PDZ domain (PDZ_2) (293-390)

• Peptidase family M50 (Peptidase_M50) (320-394)

3D structure

• AlphaFold DB: A0A9P1NK46

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.687	99.497	0.435
htrA	Streptococcus gordonii str. Challis substr. CH1	41.602	97.236	0.405
htrA	Streptococcus mitis NCTC 12261	40.26	96.734	0.389