Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   FP512_RS07285 Genome accession   NZ_CP042002
Coordinates   1447758..1449749 (-) Length   663 a.a.
NCBI ID   WP_000567075.1    Uniprot ID   Q3K051
Organism   Streptococcus agalactiae strain GBS30     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1442758..1454749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP512_RS07280 (FP512_07495) - 1446514..1447660 (+) 1147 Protein_1362 helix-turn-helix domain-containing protein -
  FP512_RS07285 (FP512_07500) uvrB 1447758..1449749 (-) 1992 WP_000567075.1 excinuclease ABC subunit UvrB Machinery gene
  FP512_RS07290 (FP512_07505) - 1449810..1450729 (-) 920 Protein_1364 CPBP family intramembrane glutamic endopeptidase -
  FP512_RS07295 (FP512_07515) - 1450912..1453095 (+) 2184 WP_000681006.1 ABC transporter substrate-binding protein/permease -
  FP512_RS07300 (FP512_07520) - 1453095..1453835 (+) 741 WP_000818887.1 amino acid ABC transporter ATP-binding protein -
  FP512_RS07305 (FP512_07525) - 1453984..1454334 (+) 351 WP_000656279.1 hypothetical protein -
  FP512_RS07310 (FP512_07530) - 1454419..1454586 (-) 168 WP_000502595.1 hypothetical protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75943.97 Da        Isoelectric Point: 4.7322

>NTDB_id=329857 FP512_RS07285 WP_000567075.1 1447758..1449749(-) (uvrB) [Streptococcus agalactiae strain GBS30]
MIDRKDTNRFKLVSKYSPSGDQPQAIETLVDNIEGGEKAQILKGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGQEISRDQLLNNLVDIQFERNDIDFQRGKFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGRVL
GEVEHLAIFPATHFMTNDEHMEEAISKIQAEMENQVELFEKEGKLIEAQRIRQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMGQTDTVVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRTEKGERTFITTLTKRMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSNGHVIMYADK
ITDSMQRAMDETARRRRLQMDYNEKHGIVPQTIKKEIRDLIAITKSNDSDKPEKVVDYSSLSKKERQAEIKALQKQMQEA
AELLDFELAAQIRDVILKLKAID

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=329857 FP512_RS07285 WP_000567075.1 1447758..1449749(-) (uvrB) [Streptococcus agalactiae strain GBS30]
ATGATAGATAGAAAAGATACTAACCGATTTAAATTAGTTTCCAAATATAGCCCTTCGGGAGATCAACCTCAAGCTATTGA
AACGTTGGTTGACAATATTGAAGGAGGAGAAAAAGCTCAGATTTTAAAAGGTGCTACTGGTACTGGTAAAACCTACACAA
TGAGCCAAGTTATCGCCCAAGTTAACAAGCCAACCTTGGTGATTGCACATAATAAAACCTTAGCAGGTCAACTTTATGGA
GAGTTTAAAGAATTTTTTCCTGACAATGCCGTAGAGTACTTTGTTTCATATTATGATTATTATCAACCAGAAGCTTATGT
GCCTTCTTCGGATACTTATATTGAAAAAGATAGTTCAGTCAATGACGAAATTGACAAATTACGTCACTCAGCGACTTCTT
CGTTATTAGAAAGAAATGACGTTATTGTTGTAGCATCTGTTTCTTGTATTTACGGTTTAGGTTCTCCTAAAGAGTATGCA
GACAGTGTTGTTAGCCTTAGGCCAGGTCAAGAAATTTCACGTGATCAGTTATTGAACAATCTCGTTGATATTCAATTTGA
GCGTAACGATATTGATTTTCAACGTGGAAAATTTCGCGTTCGTGGCGATGTTGTAGAAGTTTTTCCTGCGAGTCGTGATG
AGCATGCCTTTCGAATTGAATTTTTTGGTGATGAAATTGATCGTATAAGAGAAATAGAATCGTTAACAGGGCGTGTGCTA
GGAGAAGTGGAACATTTAGCTATTTTCCCAGCAACACACTTTATGACAAATGATGAACATATGGAAGAAGCTATTTCAAA
AATACAAGCTGAAATGGAAAATCAAGTAGAACTTTTTGAAAAAGAAGGGAAATTGATTGAAGCGCAACGTATTCGACAAA
GGACAGAATATGATATTGAAATGCTTCGTGAAATGGGATATACAAATGGTGTTGAGAACTACTCACGTCACATGGATGGT
AGAAGTGAAGGTGAGCCACCTTTTACTTTGTTAGATTTCTTCCCAGAAGATTTTTTGATTATGATTGATGAGAGTCACAT
GACAATGGGGCAAATCAAAGGGATGTATAATGGAGACCGTTCGCGTAAAGAAATGTTGGTTAATTACGGTTTTCGTTTAC
CATCTGCCTTAGATAACCGTCCACTTCGTCGTGAAGAATTCGAAAGCCATGTCCATCAAATTGTCTATGTATCTGCAACG
CCAGGAGACTATGAAATGGGGCAAACAGATACGGTTGTTGAGCAAATTATCCGGCCAACAGGACTTCTTGATCCAGAAGT
TGAAGTTAGACCAAGTATGGGGCAGATGGATGACTTGCTTGGTGAAATCAATTTGAGGACTGAAAAAGGTGAGCGTACCT
TTATTACAACATTGACAAAGCGCATGGCAGAAGACTTAACAGATTATCTCAAAGAAATGGGAGTTAAAGTTAAGTATATG
CACAGCGATATTAAAACCTTAGAACGTACAGAGATTATTCGTGATTTACGACTTGGTGTGTTTGATGTTTTAATTGGTAT
TAATCTCTTACGTGAAGGAATAGATGTTCCTGAGGTTTCCCTTGTTGCAATCTTAGATGCTGATAAGGAAGGTTTCCTTC
GTAATGAGCGTGGTCTTATCCAAACAATCGGACGTGCAGCACGTAACAGTAATGGTCATGTTATTATGTATGCTGATAAA
ATAACAGATTCTATGCAAAGAGCTATGGATGAAACCGCTCGCCGTCGTCGTTTACAAATGGATTATAATGAAAAGCATGG
AATTGTGCCACAAACAATTAAAAAAGAAATCCGTGATTTAATTGCTATTACTAAAAGTAATGACAGCGATAAACCTGAAA
AAGTTGTCGATTACAGTAGTTTATCTAAGAAAGAAAGGCAAGCTGAAATTAAAGCTCTTCAAAAGCAAATGCAAGAAGCA
GCTGAATTATTGGACTTTGAGCTAGCTGCACAAATCCGAGATGTTATCTTAAAACTAAAAGCAATCGATTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Type III restriction enzyme, res subunit (ResIII)

(20-143)

UvrB interaction domain (UvrB_inter)

(164-254)

UvrB/uvrC motif (UVR)

(628-661)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3K051

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

87.029

100

0.87
  uvrB Streptococcus pneumoniae D39

87.029

100

0.87
  uvrB Streptococcus pneumoniae TIGR4

86.878

100

0.869