Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SUB_RS04815 Genome accession   NC_012004
Coordinates   934564..935874 (-) Length   436 a.a.
NCBI ID   WP_012658456.1    Uniprot ID   B9DS98
Organism   Streptococcus uberis 0140J     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 929564..940874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS04785 (SUB0951) - 930088..930474 (-) 387 WP_012658450.1 cytidine deaminase -
  SUB_RS04790 (SUB0952) deoC 930464..931126 (-) 663 WP_012658451.1 deoxyribose-phosphate aldolase -
  SUB_RS04795 (SUB0953) - 931137..932414 (-) 1278 WP_012658452.1 pyrimidine-nucleoside phosphorylase -
  SUB_RS04800 (SUB0954) - 932411..933001 (-) 591 WP_012658453.1 class I SAM-dependent methyltransferase -
  SUB_RS04805 (SUB0955) coaA 933265..934185 (+) 921 WP_012658454.1 type I pantothenate kinase -
  SUB_RS04810 (SUB0956) rpsT 934245..934487 (+) 243 WP_160463058.1 30S ribosomal protein S20 -
  SUB_RS04815 (SUB0957) ciaH 934564..935874 (-) 1311 WP_012658456.1 sensor histidine kinase Regulator
  SUB_RS04820 (SUB0958) ciaR 935867..936541 (-) 675 WP_012658457.1 response regulator transcription factor Regulator
  SUB_RS04825 (SUB0959) - 936663..939200 (-) 2538 WP_012658458.1 M1 family metallopeptidase -
  SUB_RS04830 (SUB0960) phoU 939270..939923 (-) 654 WP_012658459.1 phosphate signaling complex protein PhoU -
  SUB_RS04835 (SUB0961) pstB 939943..940701 (-) 759 WP_012658460.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 50077.08 Da        Isoelectric Point: 7.2492

>NTDB_id=32929 SUB_RS04815 WP_012658456.1 934564..935874(-) (ciaH) [Streptococcus uberis 0140J]
MTKYKELLKSDNFNHFSHYFSVFTGIFVVMTFIILQIMKFGVYSSVDSSLLTVAKNSENYTNKTMERISSFYFDNQSGHF
KASTEAFKIKNDNEPVANTDILLFSSNGIVINSFDALSNFQNFTLNKNELNTIQTQKLVNYYGHEEKFHTITVRVHSKNY
PAIAYMMAVVNVEQSEKTNERYEKFIIIVMIVFWLISIIASIYLANWSSKPIIESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNESILDNSEAIASSLDEVRNMRILTTNLLNLARRDDGIKPDWEEIDAQFFNGIFENYSLIAEENGKSFQFDN
QVHRKVKTDKALLKQLLTILFDNAIKYTDADGEIEIQVSTGDKHLYLTVLDNGPGISDDDKKKIFDRFYRVDKARTRSKG
GFGLGLALAQQIVQSLKGSIVVKDNRPKGTIFEVKF

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=32929 SUB_RS04815 WP_012658456.1 934564..935874(-) (ciaH) [Streptococcus uberis 0140J]
ATGACTAAATATAAAGAATTACTTAAATCCGATAATTTTAATCACTTTTCCCATTATTTTTCTGTATTTACGGGCATTTT
TGTGGTTATGACTTTTATTATCCTTCAGATCATGAAATTTGGTGTCTATTCATCAGTTGATAGTAGTTTATTGACTGTTG
CCAAGAATTCAGAGAATTATACCAACAAGACCATGGAGAGAATTTCTTCCTTTTATTTTGATAACCAAAGTGGTCATTTT
AAAGCTAGTACAGAAGCATTTAAAATAAAGAATGATAATGAGCCGGTTGCAAATACAGATATCTTACTCTTTAGTTCAAA
CGGTATTGTTATCAACAGTTTTGATGCGCTTTCCAATTTTCAAAATTTTACGCTGAATAAAAACGAATTAAATACGATTC
AAACGCAAAAATTAGTCAATTACTATGGCCATGAAGAAAAATTTCATACCATTACAGTAAGGGTGCATTCCAAAAACTAC
CCTGCAATCGCCTATATGATGGCCGTAGTAAATGTTGAACAGTCAGAAAAAACAAATGAACGATATGAGAAATTTATCAT
AATCGTTATGATTGTGTTCTGGCTCATTTCCATTATCGCTAGTATATATCTGGCAAATTGGAGTAGTAAGCCTATCATTG
AGAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCCAGTCATGAATTAAGGACGCCTTTGGCCGTTTTACAGAATCGT
TTAGAAAGTTTATTTCGAAAGCCAAACGAGAGTATTCTTGATAATAGCGAAGCCATTGCGTCAAGCTTAGATGAAGTCAG
AAATATGAGAATACTAACCACTAATCTTCTTAATCTTGCGAGACGTGATGATGGTATAAAACCCGACTGGGAAGAAATTG
ATGCTCAATTCTTTAATGGTATTTTTGAAAATTATAGCCTTATTGCAGAAGAAAATGGCAAATCATTCCAGTTTGATAAT
CAAGTTCATAGAAAAGTAAAAACTGATAAAGCTTTACTCAAACAACTGTTAACGATTCTATTTGACAATGCCATAAAATA
TACTGATGCTGACGGTGAGATTGAAATACAGGTTTCAACTGGGGATAAACATCTCTATCTTACTGTCTTAGATAATGGAC
CTGGCATTAGTGATGATGACAAAAAGAAAATTTTTGACAGATTCTATAGAGTCGATAAAGCCAGAACAAGAAGTAAGGGT
GGATTTGGATTAGGATTAGCCTTAGCTCAACAAATCGTTCAATCTTTAAAAGGAAGTATTGTCGTTAAGGATAATAGGCC
TAAAGGGACAATTTTTGAAGTCAAATTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DS98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.11

100

0.571
  ciaH Streptococcus pneumoniae Rx1

50.805

99.771

0.507
  ciaH Streptococcus pneumoniae D39

50.805

99.771

0.507
  ciaH Streptococcus pneumoniae R6

50.805

99.771

0.507
  ciaH Streptococcus pneumoniae TIGR4

50.805

99.771

0.507

Multiple sequence alignment