Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | EGH12_RS01315 | Genome accession | NZ_CP034020 |
| Coordinates | 221888..222337 (+) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae strain FQ48 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 222586..254098 | 221888..222337 | flank | 249 |
Gene organization within MGE regions
Location: 221888..254098
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGH12_RS01315 (EGH12_01315) | comP | 221888..222337 (+) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
| EGH12_RS01325 (EGH12_01325) | - | 222714..222860 (-) | 147 | WP_003691757.1 | hypothetical protein | - |
| EGH12_RS01330 (EGH12_01330) | - | 223247..223837 (+) | 591 | WP_080229150.1 | DNA cytosine methyltransferase | - |
| EGH12_RS01335 (EGH12_01335) | - | 223834..224205 (+) | 372 | WP_012503918.1 | DNA cytosine methyltransferase | - |
| EGH12_RS14040 | - | 224219..225076 (+) | 858 | WP_012503917.1 | ATP-binding protein | - |
| EGH12_RS14045 | - | 225266..225862 (+) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| EGH12_RS01345 (EGH12_01345) | - | 225868..226290 (+) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| EGH12_RS01350 (EGH12_01350) | - | 226429..227760 (+) | 1332 | WP_050155400.1 | replication initiation factor domain-containing protein | - |
| EGH12_RS01355 (EGH12_01355) | - | 227805..228095 (+) | 291 | WP_002216601.1 | hypothetical protein | - |
| EGH12_RS01360 (EGH12_01360) | - | 228100..228297 (+) | 198 | WP_003689600.1 | hypothetical protein | - |
| EGH12_RS01365 (EGH12_01365) | - | 228371..228589 (+) | 219 | WP_003691584.1 | major capsid protein | - |
| EGH12_RS01370 (EGH12_01370) | - | 228596..228874 (+) | 279 | WP_003689168.1 | hypothetical protein | - |
| EGH12_RS01375 (EGH12_01375) | - | 229002..229319 (+) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| EGH12_RS01380 (EGH12_01380) | - | 229261..230850 (+) | 1590 | WP_165865522.1 | IgG-binding virulence factor TspB family protein | - |
| EGH12_RS01385 (EGH12_01385) | - | 230829..231119 (+) | 291 | WP_047917922.1 | DUF2523 domain-containing protein | - |
| EGH12_RS01390 (EGH12_01390) | - | 231129..232214 (+) | 1086 | WP_003700139.1 | zonular occludens toxin domain-containing protein | - |
| EGH12_RS01395 (EGH12_01395) | - | 232335..232694 (+) | 360 | WP_003689732.1 | hypothetical protein | - |
| EGH12_RS01400 (EGH12_01400) | - | 233206..234168 (+) | 963 | WP_050156280.1 | IS110-like element ISNgo2 family transposase | - |
| EGH12_RS14490 | - | 234352..234480 (+) | 129 | WP_012503747.1 | hypothetical protein | - |
| EGH12_RS01410 (EGH12_01410) | - | 234497..234877 (-) | 381 | WP_033910829.1 | RusA family crossover junction endodeoxyribonuclease | - |
| EGH12_RS14050 | - | 234868..235149 (-) | 282 | WP_003689109.1 | hypothetical protein | - |
| EGH12_RS01415 (EGH12_01415) | - | 235178..235327 (-) | 150 | WP_003689110.1 | hypothetical protein | - |
| EGH12_RS01420 (EGH12_01420) | - | 235504..235998 (-) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| EGH12_RS01425 (EGH12_01425) | - | 236037..236243 (-) | 207 | WP_044271496.1 | hypothetical protein | - |
| EGH12_RS01430 (EGH12_01430) | - | 236313..237095 (-) | 783 | WP_025456432.1 | ATP-binding protein | - |
| EGH12_RS01435 (EGH12_01435) | - | 237110..238120 (-) | 1011 | WP_050153770.1 | helix-turn-helix domain-containing protein | - |
| EGH12_RS01440 (EGH12_01440) | - | 238117..238344 (-) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| EGH12_RS01445 (EGH12_01445) | - | 238517..238705 (+) | 189 | WP_003698903.1 | hypothetical protein | - |
| EGH12_RS01450 (EGH12_01450) | - | 238682..238837 (-) | 156 | WP_003689578.1 | hypothetical protein | - |
| EGH12_RS01455 (EGH12_01455) | - | 238917..239132 (-) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| EGH12_RS01460 (EGH12_01460) | - | 239260..239964 (+) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| EGH12_RS01465 (EGH12_01465) | - | 240124..240663 (+) | 540 | WP_003695998.1 | type II toxin-antitoxin system antitoxin SocA domain-containing protein | - |
| EGH12_RS01470 (EGH12_01470) | - | 240664..241023 (+) | 360 | WP_003691733.1 | hypothetical protein | - |
| EGH12_RS01475 (EGH12_01475) | - | 241040..241258 (-) | 219 | WP_003691731.1 | hypothetical protein | - |
| EGH12_RS01480 (EGH12_01480) | - | 241742..241942 (+) | 201 | WP_047920246.1 | hypothetical protein | - |
| EGH12_RS01485 (EGH12_01485) | - | 241975..242451 (+) | 477 | WP_002255718.1 | hypothetical protein | - |
| EGH12_RS01490 (EGH12_01490) | - | 242448..242681 (+) | 234 | WP_124935080.1 | hypothetical protein | - |
| EGH12_RS01495 (EGH12_01495) | - | 242822..243154 (+) | 333 | WP_003705604.1 | hypothetical protein | - |
| EGH12_RS01500 (EGH12_01500) | - | 243307..243585 (+) | 279 | WP_003691529.1 | hypothetical protein | - |
| EGH12_RS01505 (EGH12_01505) | - | 243582..243743 (+) | 162 | WP_003693867.1 | hypothetical protein | - |
| EGH12_RS01510 (EGH12_01510) | - | 243812..244498 (+) | 687 | WP_042758540.1 | hypothetical protein | - |
| EGH12_RS01515 (EGH12_01515) | - | 244638..244820 (+) | 183 | WP_003691535.1 | hypothetical protein | - |
| EGH12_RS01520 (EGH12_01520) | - | 244817..245308 (+) | 492 | WP_047916888.1 | siphovirus Gp157 family protein | - |
| EGH12_RS01525 (EGH12_01525) | - | 245360..245575 (+) | 216 | WP_003691538.1 | hypothetical protein | - |
| EGH12_RS01530 (EGH12_01530) | - | 245686..246669 (+) | 984 | WP_047952517.1 | hypothetical protein | - |
| EGH12_RS13310 | - | 246666..246896 (+) | 231 | WP_003695893.1 | hypothetical protein | - |
| EGH12_RS01535 (EGH12_01535) | - | 246868..247815 (+) | 948 | WP_012503904.1 | hypothetical protein | - |
| EGH12_RS01540 (EGH12_01540) | - | 247923..248189 (+) | 267 | WP_003689557.1 | pyocin activator PrtN family protein | - |
| EGH12_RS01545 (EGH12_01545) | - | 248239..249393 (-) | 1155 | WP_003697468.1 | tyrosine-type recombinase/integrase | - |
| EGH12_RS01550 (EGH12_01550) | dusA | 249513..250529 (+) | 1017 | WP_003689555.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| EGH12_RS01555 (EGH12_01555) | gluQRS | 250599..251486 (-) | 888 | WP_003689554.1 | tRNA glutamyl-Q(34) synthetase GluQRS | - |
| EGH12_RS01560 (EGH12_01560) | - | 251503..251793 (-) | 291 | WP_003689553.1 | hypothetical protein | - |
| EGH12_RS14495 | - | 251798..251932 (-) | 135 | WP_012503902.1 | hypothetical protein | - |
| EGH12_RS01565 (EGH12_01565) | tal | 251944..252999 (-) | 1056 | WP_003689551.1 | transaldolase | - |
| EGH12_RS01570 (EGH12_01570) | - | 253096..254070 (+) | 975 | WP_003689550.1 | KpsF/GutQ family sugar-phosphate isomerase | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=328128 EGH12_RS01315 WP_002214937.1 221888..222337(+) (comP) [Neisseria gonorrhoeae strain FQ48]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=328128 EGH12_RS01315 WP_002214937.1 221888..222337(+) (comP) [Neisseria gonorrhoeae strain FQ48]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |