Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FNW97_RS20065 Genome accession   NZ_CP041627
Coordinates   4014772..4015362 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ETEC6     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4009772..4020362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNW97_RS20050 (FNW97_20050) uhpT 4010412..4011803 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FNW97_RS20055 (FNW97_20055) uhpC 4011941..4013260 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FNW97_RS20060 (FNW97_20060) uhpB 4013270..4014772 (-) 1503 WP_047603029.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FNW97_RS20065 (FNW97_20065) letA 4014772..4015362 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FNW97_RS20070 (FNW97_20070) ilvN 4015438..4015728 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FNW97_RS20075 (FNW97_20075) ilvB 4015732..4017420 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  FNW97_RS20080 (FNW97_20080) ivbL 4017526..4017624 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  FNW97_RS20085 (FNW97_20085) tisB 4018189..4018278 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FNW97_RS24175 ysdE 4018402..4018476 (-) 75 WP_211180519.1 protein YsdE -
  FNW97_RS20090 (FNW97_20090) emrD 4018558..4019742 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FNW97_RS20095 (FNW97_20095) yidF 4019750..4020247 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=327499 FNW97_RS20065 WP_000633668.1 4014772..4015362(-) (letA) [Escherichia coli strain ETEC6]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=327499 FNW97_RS20065 WP_000633668.1 4014772..4015362(-) (letA) [Escherichia coli strain ETEC6]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment