Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FNW97_RS18340 Genome accession   NZ_CP041627
Coordinates   3638195..3638827 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ETEC6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3633195..3643827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNW97_RS18315 (FNW97_18315) yheS 3633364..3635277 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  FNW97_RS18320 (FNW97_18320) yheT 3635277..3636299 (+) 1023 WP_000057356.1 hydrolase -
  FNW97_RS18325 (FNW97_18325) yheU 3636293..3636511 (+) 219 WP_000907085.1 YheU family protein -
  FNW97_RS18330 (FNW97_18330) prkB 3636565..3637434 (+) 870 WP_001274680.1 phosphoribulokinase -
  FNW97_RS18335 (FNW97_18335) yhfA 3637489..3637893 (-) 405 WP_001148908.1 OsmC family protein -
  FNW97_RS18340 (FNW97_18340) crp 3638195..3638827 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FNW97_RS18345 (FNW97_18345) yhfK 3638878..3640968 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  FNW97_RS18350 (FNW97_18350) argD 3641035..3642255 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FNW97_RS18355 (FNW97_18355) pabA 3642341..3642904 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  FNW97_RS18360 (FNW97_18360) fic 3642936..3643538 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  FNW97_RS18365 (FNW97_18365) yhfG 3643528..3643695 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=327491 FNW97_RS18340 WP_000242755.1 3638195..3638827(+) (crp) [Escherichia coli strain ETEC6]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=327491 FNW97_RS18340 WP_000242755.1 3638195..3638827(+) (crp) [Escherichia coli strain ETEC6]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467