Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   EG882_RS08165 Genome accession   NZ_CP033967
Coordinates   1564109..1564753 (+) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain 1B-23     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1559109..1569753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EG882_RS08135 (EG882_08135) - 1559539..1559880 (-) 342 WP_124692757.1 hypothetical protein -
  EG882_RS08145 (EG882_08145) degQ 1560345..1560485 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  EG882_RS08150 (EG882_08150) - 1560637..1561512 (+) 876 WP_025285191.1 polyprenyl synthetase family protein -
  EG882_RS08155 (EG882_08155) comX 1561527..1561703 (+) 177 WP_015240484.1 competence pheromone ComX -
  EG882_RS08160 (EG882_08160) comP 1561722..1564028 (+) 2307 WP_124692758.1 sensor histidine kinase Regulator
  EG882_RS08165 (EG882_08165) comA 1564109..1564753 (+) 645 WP_003152052.1 response regulator transcription factor Regulator
  EG882_RS08170 (EG882_08170) - 1564775..1565158 (+) 384 WP_012118312.1 hotdog fold thioesterase -
  EG882_RS08175 (EG882_08175) mnhG 1565198..1565572 (-) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  EG882_RS08180 (EG882_08180) - 1565556..1565840 (-) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  EG882_RS08185 (EG882_08185) - 1565840..1566316 (-) 477 WP_007408672.1 Na+/H+ antiporter subunit E -
  EG882_RS08190 (EG882_08190) - 1566322..1567809 (-) 1488 WP_124692759.1 Na+/H+ antiporter subunit D -
  EG882_RS08195 (EG882_08195) - 1567802..1568143 (-) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  EG882_RS08200 (EG882_08200) - 1568143..1568574 (-) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=327460 EG882_RS08165 WP_003152052.1 1564109..1564753(+) (comA) [Bacillus velezensis strain 1B-23]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=327460 EG882_RS08165 WP_003152052.1 1564109..1564753(+) (comA) [Bacillus velezensis strain 1B-23]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGACAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment