Detailed information NTG0326363

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EGY29_RS05765
• Genome accession: NZ_CP033843
• Coordinates: 1209170..1210507 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain FDAARGOS_501
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1204170..1215507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGY29_RS05740 (EGY29_05730)	pgeF	1204313..1205041 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
EGY29_RS05745 (EGY29_05735)	rluD	1205038..1206000 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EGY29_RS05750 (EGY29_05740)	-	1206146..1207171 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
EGY29_RS05755 (EGY29_05745)	-	1207328..1207573 (+)	246	WP_014603563.1	PP0621 family protein	-
EGY29_RS05760 (EGY29_05750)	pilS	1207563..1209155 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EGY29_RS05765 (EGY29_05755)	pilR	1209170..1210507 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EGY29_RS05770 (EGY29_05760)	thiO	1210553..1211647 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
EGY29_RS05775 (EGY29_05765)	-	1211782..1212291 (+)	510	WP_015503652.1	Tfp pilus assembly protein FimT/FimU	-
EGY29_RS05780 (EGY29_05770)	-	1212397..1212903 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
EGY29_RS05785 (EGY29_05775)	pilV	1212894..1213451 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
EGY29_RS05790 (EGY29_05780)	pilW	1213448..1214272 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
EGY29_RS05795 (EGY29_05785)	pilX	1214269..1214856 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=326363 EGY29_RS05765 WP_003094694.1 1209170..1210507(+) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_501]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=326363 EGY29_RS05765 WP_003094694.1 1209170..1210507(+) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_501]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384