Detailed information NTG0326269

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EGY26_RS09150
• Genome accession: NZ_CP033833
• Coordinates: 1854846..1856183 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain FDAARGOS_571
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1849846..1861183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGY26_RS09125 (EGY26_09100)	pgeF	1849989..1850717 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
EGY26_RS09130 (EGY26_09105)	rluD	1850714..1851676 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EGY26_RS09135 (EGY26_09110)	-	1851822..1852847 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
EGY26_RS09140 (EGY26_09115)	-	1853004..1853249 (+)	246	WP_014603563.1	PP0621 family protein	-
EGY26_RS09145 (EGY26_09120)	pilS	1853239..1854831 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EGY26_RS09150 (EGY26_09125)	pilR	1854846..1856183 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EGY26_RS09155 (EGY26_09130)	thiO	1856229..1857323 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
EGY26_RS09160 (EGY26_09135)	-	1857458..1857967 (+)	510	WP_015503652.1	Tfp pilus assembly protein FimT/FimU	-
EGY26_RS09165 (EGY26_09140)	-	1858073..1858579 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
EGY26_RS09170 (EGY26_09145)	pilV	1858570..1859127 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
EGY26_RS09175 (EGY26_09150)	pilW	1859124..1859948 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
EGY26_RS09180 (EGY26_09155)	pilX	1859945..1860532 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=326269 EGY26_RS09150 WP_003094694.1 1854846..1856183(+) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_571]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=326269 EGY26_RS09150 WP_003094694.1 1854846..1856183(+) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_571]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384