Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FNE85_RS00175 Genome accession   NZ_CP041425
Coordinates   33708..34298 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain STEC388     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28708..39298
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNE85_RS00145 (FNE85_00145) yidF 28824..29321 (+) 498 WP_096129343.1 radical SAM protein -
  FNE85_RS00150 (FNE85_00150) emrD 29329..30513 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  FNE85_RS25975 ysdE 30595..30669 (+) 75 WP_213061010.1 hypothetical protein -
  FNE85_RS00155 (FNE85_00155) tisB 30793..30882 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FNE85_RS00160 (FNE85_00160) ivbL 31447..31545 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  FNE85_RS00165 (FNE85_00165) ilvB 31651..33339 (+) 1689 WP_000168461.1 acetolactate synthase large subunit -
  FNE85_RS00170 (FNE85_00170) ilvN 33343..33633 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FNE85_RS00175 (FNE85_00175) letA 33708..34298 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FNE85_RS00180 (FNE85_00180) uhpB 34298..35800 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FNE85_RS00185 (FNE85_00185) uhpC 35810..37129 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FNE85_RS00190 (FNE85_00190) uhpT 37267..38658 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=326156 FNE85_RS00175 WP_000633668.1 33708..34298(+) (letA) [Escherichia coli strain STEC388]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=326156 FNE85_RS00175 WP_000633668.1 33708..34298(+) (letA) [Escherichia coli strain STEC388]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment