Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EGX64_RS12670 Genome accession   NZ_CP033782
Coordinates   2529991..2530620 (-) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain FDAARGOS_529     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2524991..2535620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX64_RS12640 (EGX64_12635) - 2525383..2525913 (-) 531 WP_002447436.1 acyl-CoA thioesterase -
  EGX64_RS12645 (EGX64_12640) - 2525994..2527235 (-) 1242 WP_099774840.1 aminopeptidase -
  EGX64_RS12650 (EGX64_12645) - 2527237..2527452 (-) 216 WP_001830421.1 DUF1128 domain-containing protein -
  EGX64_RS12655 (EGX64_12650) - 2527594..2528058 (+) 465 WP_002458546.1 low molecular weight protein-tyrosine-phosphatase -
  EGX64_RS12660 (EGX64_12655) - 2528066..2528350 (+) 285 WP_002447438.1 YtxH domain-containing protein -
  EGX64_RS12665 (EGX64_12660) - 2528756..2529934 (+) 1179 WP_002458547.1 YihY/virulence factor BrkB family protein -
  EGX64_RS12670 (EGX64_12665) vraR 2529991..2530620 (-) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  EGX64_RS12675 (EGX64_12670) vraS 2530610..2531656 (-) 1047 WP_002447441.1 sensor histidine kinase Regulator
  EGX64_RS12680 (EGX64_12675) liaF 2531653..2532354 (-) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  EGX64_RS12685 (EGX64_12680) - 2532369..2532755 (-) 387 WP_162153127.1 hypothetical protein -
  EGX64_RS12690 (EGX64_12685) map 2532913..2533668 (-) 756 WP_002447444.1 type I methionyl aminopeptidase -
  EGX64_RS12695 (EGX64_12690) - 2533842..2534828 (+) 987 WP_002447445.1 aromatic acid exporter family protein -
  EGX64_RS12700 (EGX64_12695) - 2534981..2535517 (-) 537 WP_099774844.1 hypothetical protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=325694 EGX64_RS12670 WP_002473914.1 2529991..2530620(-) (vraR) [Staphylococcus epidermidis strain FDAARGOS_529]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=325694 EGX64_RS12670 WP_002473914.1 2529991..2530620(-) (vraR) [Staphylococcus epidermidis strain FDAARGOS_529]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment