Detailed information NTG0325695

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EGX64_RS12675
• Genome accession: NZ_CP033782
• Coordinates: 2530610..2531656 (-)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain FDAARGOS_529
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2525610..2536656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX64_RS12645 (EGX64_12640)	-	2525994..2527235 (-)	1242	WP_099774840.1	aminopeptidase	-
EGX64_RS12650 (EGX64_12645)	-	2527237..2527452 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
EGX64_RS12655 (EGX64_12650)	-	2527594..2528058 (+)	465	WP_002458546.1	low molecular weight protein-tyrosine-phosphatase	-
EGX64_RS12660 (EGX64_12655)	-	2528066..2528350 (+)	285	WP_002447438.1	YtxH domain-containing protein	-
EGX64_RS12665 (EGX64_12660)	-	2528756..2529934 (+)	1179	WP_002458547.1	YihY/virulence factor BrkB family protein	-
EGX64_RS12670 (EGX64_12665)	vraR	2529991..2530620 (-)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
EGX64_RS12675 (EGX64_12670)	vraS	2530610..2531656 (-)	1047	WP_002447441.1	sensor histidine kinase	Regulator
EGX64_RS12680 (EGX64_12675)	liaF	2531653..2532354 (-)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
EGX64_RS12685 (EGX64_12680)	-	2532369..2532755 (-)	387	WP_162153127.1	hypothetical protein	-
EGX64_RS12690 (EGX64_12685)	map	2532913..2533668 (-)	756	WP_002447444.1	type I methionyl aminopeptidase	-
EGX64_RS12695 (EGX64_12690)	-	2533842..2534828 (+)	987	WP_002447445.1	aromatic acid exporter family protein	-
EGX64_RS12700 (EGX64_12695)	-	2534981..2535517 (-)	537	WP_099774844.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=325695 EGX64_RS12675 WP_002447441.1 2530610..2531656(-) (vraS) [Staphylococcus epidermidis strain FDAARGOS_529]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=325695 EGX64_RS12675 WP_002447441.1 2530610..2531656(-) (vraS) [Staphylococcus epidermidis strain FDAARGOS_529]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACTATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCAAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914