Detailed information NTG0325597

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EGY18_RS16455
• Genome accession: NZ_CP033771
• Coordinates: 3431243..3432580 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain FDAARGOS_532
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 3426243..3437580

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGY18_RS16430 (EGY18_16370)	pgeF	3426386..3427114 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
EGY18_RS16435 (EGY18_16375)	rluD	3427111..3428073 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EGY18_RS16440 (EGY18_16380)	-	3428219..3429244 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EGY18_RS16445 (EGY18_16385)	-	3429401..3429646 (+)	246	WP_003102591.1	PP0621 family protein	-
EGY18_RS16450 (EGY18_16390)	pilS	3429636..3431228 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
EGY18_RS16455 (EGY18_16395)	pilR	3431243..3432580 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EGY18_RS16460 (EGY18_16400)	thiO	3432626..3433720 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
EGY18_RS16465 (EGY18_16405)	-	3433855..3434364 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
EGY18_RS16470 (EGY18_16410)	-	3434470..3434976 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
EGY18_RS16475 (EGY18_16415)	pilV	3434967..3435524 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EGY18_RS16480 (EGY18_16420)	pilW	3435521..3436345 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EGY18_RS16485 (EGY18_16425)	pilX	3436342..3436929 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=325597 EGY18_RS16455 WP_003094694.1 3431243..3432580(+) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_532]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=325597 EGY18_RS16455 WP_003094694.1 3431243..3432580(+) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_532]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCTCAGCG
TCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384