Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EGX83_RS03165 Genome accession   NZ_CP033768
Coordinates   670844..671551 (-) Length   235 a.a.
NCBI ID   WP_000203217.1    Uniprot ID   -
Organism   Acinetobacter baumannii strain FDAARGOS_533     
Function   regulate competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 631269..674991 670844..671551 within 0
IScluster/Tn 671830..673049 670844..671551 flank 279


Gene organization within MGE regions


Location: 631269..674991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX83_RS02945 (EGX83_02945) - 631269..631484 (-) 216 WP_000362184.1 hypothetical protein -
  EGX83_RS02950 (EGX83_02950) - 631486..631743 (-) 258 WP_000015931.1 hypothetical protein -
  EGX83_RS18695 - 631747..631908 (-) 162 WP_171411503.1 hypothetical protein -
  EGX83_RS02955 (EGX83_02955) - 632083..632373 (+) 291 WP_123793622.1 hypothetical protein -
  EGX83_RS02960 (EGX83_02960) - 632370..633923 (+) 1554 WP_123793624.1 DNA cytosine methyltransferase -
  EGX83_RS02965 (EGX83_02965) - 633920..634870 (+) 951 WP_032059719.1 YdaU family protein -
  EGX83_RS02970 (EGX83_02970) - 634863..635612 (+) 750 WP_086264291.1 hypothetical protein -
  EGX83_RS02975 (EGX83_02975) - 635609..635737 (+) 129 WP_001031747.1 putative phage replication protein -
  EGX83_RS02980 (EGX83_02980) - 635730..635936 (+) 207 WP_000030899.1 hypothetical protein -
  EGX83_RS02985 (EGX83_02985) - 635926..636249 (+) 324 WP_000378367.1 hypothetical protein -
  EGX83_RS02990 (EGX83_02990) - 636249..636644 (+) 396 WP_123793626.1 DUF559 domain-containing protein -
  EGX83_RS02995 (EGX83_02995) - 636641..637129 (+) 489 WP_000783468.1 hypothetical protein -
  EGX83_RS03000 (EGX83_03000) - 637159..638508 (+) 1350 WP_000985644.1 ATP-binding protein -
  EGX83_RS03005 (EGX83_03005) - 638749..638931 (+) 183 WP_002056361.1 hypothetical protein -
  EGX83_RS03010 (EGX83_03010) - 638983..639201 (+) 219 WP_001017705.1 hypothetical protein -
  EGX83_RS18845 - 639269..639427 (+) 159 Protein_578 hypothetical protein -
  EGX83_RS03015 (EGX83_03015) - 639636..639872 (+) 237 WP_123793628.1 hypothetical protein -
  EGX83_RS03020 (EGX83_03020) - 640534..640989 (+) 456 WP_000195750.1 hypothetical protein -
  EGX83_RS03025 (EGX83_03025) - 641050..641517 (+) 468 WP_000378515.1 hypothetical protein -
  EGX83_RS03030 (EGX83_03030) - 641486..642127 (+) 642 WP_000372128.1 putative metallopeptidase -
  EGX83_RS03035 (EGX83_03035) - 642186..642656 (+) 471 WP_000212566.1 DUF2280 domain-containing protein -
  EGX83_RS03040 (EGX83_03040) terL 642646..644073 (+) 1428 WP_049594624.1 phage terminase large subunit -
  EGX83_RS03045 (EGX83_03045) - 644070..645521 (+) 1452 WP_104039407.1 DUF4055 domain-containing protein -
  EGX83_RS03050 (EGX83_03050) - 645523..646626 (+) 1104 WP_123793630.1 minor capsid protein -
  EGX83_RS03055 (EGX83_03055) - 646749..647114 (+) 366 WP_123793632.1 hypothetical protein -
  EGX83_RS03060 (EGX83_03060) - 647101..647442 (+) 342 WP_031975096.1 phage tail protein -
  EGX83_RS03065 (EGX83_03065) - 647496..648389 (+) 894 WP_123793634.1 pyocin knob domain-containing protein -
  EGX83_RS03070 (EGX83_03070) - 648376..649182 (+) 807 WP_123793636.1 phage minor tail protein L -
  EGX83_RS03075 (EGX83_03075) - 649189..649944 (+) 756 WP_000778490.1 C40 family peptidase -
  EGX83_RS03080 (EGX83_03080) - 649928..650593 (+) 666 WP_000920725.1 tail assembly protein -
  EGX83_RS03085 (EGX83_03085) - 650650..654483 (+) 3834 Protein_593 host specificity protein J -
  EGX83_RS03090 (EGX83_03090) - 654613..654972 (+) 360 WP_002051633.1 hypothetical protein -
  EGX83_RS03095 (EGX83_03095) - 654953..655804 (+) 852 WP_126065006.1 hypothetical protein -
  EGX83_RS03100 (EGX83_03100) - 655891..656184 (+) 294 WP_000999698.1 phage holin -
  EGX83_RS03105 (EGX83_03105) - 656165..656389 (+) 225 WP_000200152.1 hypothetical protein -
  EGX83_RS03110 (EGX83_03110) - 656446..656991 (+) 546 WP_123793638.1 glycoside hydrolase family 108 protein -
  EGX83_RS03115 (EGX83_03115) - 657136..657909 (-) 774 WP_001066070.1 membrane protein -
  EGX83_RS03120 (EGX83_03120) - 658088..659734 (+) 1647 WP_123793640.1 phosphoethanolamine transferase -
  EGX83_RS03125 (EGX83_03125) - 659993..661195 (-) 1203 WP_123090721.1 tyrosine-type recombinase/integrase -
  EGX83_RS03130 (EGX83_03130) alaS 661482..664118 (-) 2637 WP_032059901.1 alanine--tRNA ligase -
  EGX83_RS03135 (EGX83_03135) - 664388..665413 (+) 1026 WP_001188816.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  EGX83_RS03140 (EGX83_03140) - 665689..666855 (+) 1167 WP_000155682.1 ATP phosphoribosyltransferase regulatory subunit -
  EGX83_RS03145 (EGX83_03145) - 666920..668239 (+) 1320 WP_000517792.1 adenylosuccinate synthase -
  EGX83_RS03150 (EGX83_03150) - 668362..668679 (+) 318 WP_000776215.1 hypothetical protein -
  EGX83_RS03155 (EGX83_03155) - 668796..669575 (+) 780 WP_001034598.1 M48 family metallopeptidase -
  EGX83_RS03160 (EGX83_03160) - 669634..670683 (-) 1050 WP_032059899.1 NADP(H)-dependent aldo-keto reductase -
  EGX83_RS03165 (EGX83_03165) crp 670844..671551 (-) 708 WP_000203217.1 cAMP-activated global transcriptional regulator CRP Regulator
  EGX83_RS03175 (EGX83_03175) - 673104..673223 (+) 120 Protein_611 hypothetical protein -
  EGX83_RS03180 (EGX83_03180) - 673302..673724 (+) 423 WP_001195082.1 OsmC family protein -
  EGX83_RS03185 (EGX83_03185) - 673817..674242 (+) 426 WP_001026231.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26567.18 Da        Isoelectric Point: 4.6625

>NTDB_id=325540 EGX83_RS03165 WP_000203217.1 670844..671551(-) (crp) [Acinetobacter baumannii strain FDAARGOS_533]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFDTSLEETPVTDEDYDDEE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=325540 EGX83_RS03165 WP_000203217.1 670844..671551(-) (crp) [Acinetobacter baumannii strain FDAARGOS_533]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCTCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCCGGAACAGAGTCAAAATCTTTATATTTAATTT
TAAAAGGCTCAGTTTCAATTATTTTACGTGAAGACGATGAACGTGAAATTGTTGTGGCATATTTGAATCCTGGTGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACCCGTGATGTCTGTGAAATTGCGGA
AATTTCATATGACAACTTCCACGAACTGAGCAAACAGTATCCAGATCTCAGCTATGCCGTTTTCGCGCAACTCGTTCGTC
GTTTAAAAAATACAACTCGTAAAATGACCGATCTTGCATTTATTGATGTGTCAGGTCGTATTGCGCGTTGCTTAATCGAC
CTATCTTCACAACCAGAAGCAATGATCTTGCCGAATGGCCGTCAAATTCGTATTACTCGACAAGAGATTGGACGCATTGT
CGGGTGTTCACGAGAAATGGTTGGCCGTGTATTAAAGACCTTAGAAGATCAAGGTATGATTCAAACTGACGGTAAAGCTA
TTCTAATTTTTGATACTTCATTAGAAGAAACCCCAGTCACTGACGAAGACTACGATGACGAAGAATAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(152-218)

Cyclic nucleotide-binding domain (cNMP_binding)

(33-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Acinetobacter baumannii D1279779

99.574

100

0.996
  crp Vibrio cholerae strain A1552

47.343

88.085

0.417
  crp Haemophilus influenzae Rd KW20

48.705

82.128

0.4

Multiple sequence alignment