Detailed information NTG0325506

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EGX78_RS02425
• Genome accession: NZ_CP033767
• Coordinates: 446139..447140 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain FDAARGOS_534
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 441139..452140

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX78_RS02400 (EGX78_02405)	-	441813..442496 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
EGX78_RS02405 (EGX78_02410)	-	442707..443633 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
EGX78_RS02410 (EGX78_02415)	-	443778..444155 (-)	378	WP_002985686.1	VOC family protein	-
EGX78_RS02415 (EGX78_02420)	-	444166..444831 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
EGX78_RS02420 (EGX78_02425)	-	444880..445965 (-)	1086	WP_002990707.1	Xaa-Pro peptidase family protein	-
EGX78_RS02425 (EGX78_02430)	ccpA	446139..447140 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EGX78_RS02430 (EGX78_02435)	-	447271..448269 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
EGX78_RS02435 (EGX78_02440)	-	448271..449605 (+)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
EGX78_RS02440 (EGX78_02445)	thrS	450027..451970 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=325506 EGX78_RS02425 WP_002985680.1 446139..447140(+) (ccpA) [Streptococcus pyogenes strain FDAARGOS_534]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=325506 EGX78_RS02425 WP_002985680.1 446139..447140(+) (ccpA) [Streptococcus pyogenes strain FDAARGOS_534]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559