Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FK544_RS01155 Genome accession   NZ_CP041304
Coordinates   29082..29672 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain MSHS 133     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 24082..34672
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FK544_RS01125 (FK544_01120) yidF 24201..24698 (+) 498 WP_000148034.1 radical SAM protein -
  FK544_RS01130 (FK544_01125) emrD 24706..25890 (-) 1185 WP_001696327.1 multidrug efflux MFS transporter EmrD -
  FK544_RS25740 ysdE 25972..26046 (+) 75 WP_211180519.1 protein YsdE -
  FK544_RS01135 (FK544_01130) tisB 26170..26259 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FK544_RS01140 (FK544_01135) ivbL 26823..26921 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  FK544_RS01145 (FK544_01140) ilvB 27027..28715 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  FK544_RS01150 (FK544_01145) ilvN 28719..29009 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FK544_RS01155 (FK544_01150) letA 29082..29672 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FK544_RS01160 (FK544_01155) uhpB 29672..31174 (+) 1503 WP_001318135.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FK544_RS01165 (FK544_01160) uhpC 31184..32503 (+) 1320 WP_001696326.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FK544_RS01170 (FK544_01165) uhpT 32759..34150 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=325341 FK544_RS01155 WP_000633668.1 29082..29672(+) (letA) [Escherichia coli strain MSHS 133]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=325341 FK544_RS01155 WP_000633668.1 29082..29672(+) (letA) [Escherichia coli strain MSHS 133]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment