Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EGX68_RS08350 Genome accession   NZ_CP033735
Coordinates   1617962..1618591 (-) Length   209 a.a.
NCBI ID   WP_019469616.1    Uniprot ID   A0A6N7XUN7
Organism   Staphylococcus cohnii strain FDAARGOS_538     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1612962..1623591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX68_RS08320 (EGX68_08325) - 1613457..1613978 (-) 522 WP_103211098.1 acyl-CoA thioesterase -
  EGX68_RS08325 (EGX68_08330) - 1614137..1615375 (-) 1239 WP_019469621.1 aminopeptidase -
  EGX68_RS08330 (EGX68_08335) - 1615390..1615593 (-) 204 WP_019469620.1 DUF1128 family protein -
  EGX68_RS08335 (EGX68_08340) - 1615726..1616190 (+) 465 WP_019469619.1 low molecular weight protein-tyrosine-phosphatase -
  EGX68_RS08340 (EGX68_08345) - 1616198..1616482 (+) 285 WP_103211099.1 hypothetical protein -
  EGX68_RS08345 (EGX68_08350) - 1616795..1617874 (+) 1080 WP_019469617.1 YihY/virulence factor BrkB family protein -
  EGX68_RS08350 (EGX68_08355) vraR 1617962..1618591 (-) 630 WP_019469616.1 response regulator transcription factor Regulator
  EGX68_RS08355 (EGX68_08360) vraS 1618581..1619624 (-) 1044 WP_019469615.1 sensor histidine kinase Regulator
  EGX68_RS08360 (EGX68_08365) liaF 1619621..1620322 (-) 702 WP_019469614.1 cell wall-active antibiotics response protein LiaF -
  EGX68_RS08365 (EGX68_08370) - 1620339..1620725 (-) 387 WP_019469613.1 hypothetical protein -
  EGX68_RS08370 (EGX68_08375) map 1620830..1621582 (-) 753 WP_019469612.1 type I methionyl aminopeptidase -
  EGX68_RS08375 (EGX68_08380) - 1621759..1622745 (+) 987 WP_019469611.1 aromatic acid exporter family protein -
  EGX68_RS08380 (EGX68_08385) - 1622839..1623561 (-) 723 WP_019469610.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23774.31 Da        Isoelectric Point: 4.7152

>NTDB_id=325195 EGX68_RS08350 WP_019469616.1 1617962..1618591(-) (vraR) [Staphylococcus cohnii strain FDAARGOS_538]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGQSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYRDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNVLSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=325195 EGX68_RS08350 WP_019469616.1 1617962..1618591(-) (vraR) [Staphylococcus cohnii strain FDAARGOS_538]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAGATGGTCAGAATTGGTATTTCTAGTTATTTATCTACTCAACCAGA
TATAGAAGTAGTCGGAGAAGGGCAATCGGGTAAAGATGCAATTGAAAAAGCACATGAACTAAAACCTGATTTAATTTTAA
TGGACTTACTGATGGATGATATGGATGGCGTAGAAGCTACAGAACAAATTAAGAAAGATTTGCCACACATTAAAGTTGTT
ATGCTAACAAGTTATATTGAAGATAATGAAGTGTACCGCGCGCTAGATTCTGGTGTAGATAGCTATATTTTAAAAACAAC
AAGTGCCAGTGATATCGCTGAAGCAATACGCAAAACATATCGTGATGAATCTGTATTTGAAGCAGAAGTGTTGGTTAAAA
TGAGAAATCGTATGAAACAACGCGCTGAATTATATGAGATGTTAACTGAACGTGAAATGGAAATATTATTATTGATTGCA
AAAGGGTACTCAAACCAAGAAATTGCCAGTGCTTCACATATTACAATCAAAACAGTTAAAACACATGTGAGTAACGTATT
GAGTAAATTAGAAGTACAAGATAGAACTCAAGCTGTAATCTATGCATTTCAACATAATTTAATACAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N7XUN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364

Multiple sequence alignment