Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EGX58_RS08695 Genome accession   NZ_CP033732
Coordinates   1729759..1730388 (+) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis strain FDAARGOS_575     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1724759..1735388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX58_RS08670 (EGX58_08680) map 1725579..1726331 (+) 753 WP_002455125.1 type I methionyl aminopeptidase -
  EGX58_RS08675 (EGX58_08685) - 1726380..1727390 (-) 1011 WP_002455126.1 HoxN/HupN/NixA family nickel/cobalt transporter -
  EGX58_RS08680 (EGX58_08690) - 1727618..1728004 (+) 387 WP_002455127.1 hypothetical protein -
  EGX58_RS08685 (EGX58_08695) liaF 1728025..1728726 (+) 702 WP_002450089.1 cell wall-active antibiotics response protein LiaF -
  EGX58_RS08690 (EGX58_08700) vraS 1728723..1729757 (+) 1035 WP_002450020.1 sensor histidine kinase Regulator
  EGX58_RS08695 (EGX58_08705) vraR 1729759..1730388 (+) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  EGX58_RS08700 (EGX58_08710) - 1730468..1731676 (-) 1209 WP_002455128.1 YihY/virulence factor BrkB family protein -
  EGX58_RS08705 (EGX58_08715) - 1731768..1732049 (-) 282 WP_002450075.1 hypothetical protein -
  EGX58_RS08710 (EGX58_08720) - 1732055..1732519 (-) 465 WP_002455129.1 low molecular weight protein-tyrosine-phosphatase -
  EGX58_RS08715 (EGX58_08725) - 1732661..1732867 (+) 207 WP_002450082.1 DUF1128 domain-containing protein -
  EGX58_RS08720 (EGX58_08730) - 1732879..1734126 (+) 1248 WP_103288029.1 aminopeptidase -
  EGX58_RS08725 (EGX58_08735) - 1734159..1734692 (+) 534 WP_002450051.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=325158 EGX58_RS08695 WP_002450048.1 1729759..1730388(+) (vraR) [Staphylococcus hominis strain FDAARGOS_575]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=325158 EGX58_RS08695 WP_002450048.1 1729759..1730388(+) (vraR) [Staphylococcus hominis strain FDAARGOS_575]
ATGACGATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGGGAAGGATCATCAGGAAAAGAGGCAATCGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCACATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGGGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCAAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTTGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment