Detailed information NTG0325157

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EGX58_RS08690
• Genome accession: NZ_CP033732
• Coordinates: 1728723..1729757 (+)
• Length: 344 a.a.
• NCBI ID: WP_002450020.1
• Uniprot ID: -
• Organism: Staphylococcus hominis strain FDAARGOS_575
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1723723..1734757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX58_RS08665 (EGX58_08675)	-	1724416..1725405 (-)	990	WP_049438092.1	FUSC family protein	-
EGX58_RS08670 (EGX58_08680)	map	1725579..1726331 (+)	753	WP_002455125.1	type I methionyl aminopeptidase	-
EGX58_RS08675 (EGX58_08685)	-	1726380..1727390 (-)	1011	WP_002455126.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
EGX58_RS08680 (EGX58_08690)	-	1727618..1728004 (+)	387	WP_002455127.1	hypothetical protein	-
EGX58_RS08685 (EGX58_08695)	liaF	1728025..1728726 (+)	702	WP_002450089.1	cell wall-active antibiotics response protein LiaF	-
EGX58_RS08690 (EGX58_08700)	vraS	1728723..1729757 (+)	1035	WP_002450020.1	sensor histidine kinase	Regulator
EGX58_RS08695 (EGX58_08705)	vraR	1729759..1730388 (+)	630	WP_002450048.1	two-component system response regulator VraR	Regulator
EGX58_RS08700 (EGX58_08710)	-	1730468..1731676 (-)	1209	WP_002455128.1	YihY/virulence factor BrkB family protein	-
EGX58_RS08705 (EGX58_08715)	-	1731768..1732049 (-)	282	WP_002450075.1	hypothetical protein	-
EGX58_RS08710 (EGX58_08720)	-	1732055..1732519 (-)	465	WP_002455129.1	low molecular weight protein-tyrosine-phosphatase	-
EGX58_RS08715 (EGX58_08725)	-	1732661..1732867 (+)	207	WP_002450082.1	DUF1128 domain-containing protein	-
EGX58_RS08720 (EGX58_08730)	-	1732879..1734126 (+)	1248	WP_103288029.1	aminopeptidase	-
EGX58_RS08725 (EGX58_08735)	-	1734159..1734692 (+)	534	WP_002450051.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 344 a.a.
• Molecular weight: 39657.23 Da
• Isoelectric Point: 6.3137

>NTDB_id=325157 EGX58_RS08690 WP_002450020.1 1728723..1729757(+) (vraS) [Staphylococcus hominis strain FDAARGOS_575]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSVLAYKINQQNDWIKN
QIEHAIEGETVGINDKNIELYNETIDIYQMLVPLNQELQRLRIKTQNLTNENYNMNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELAPPLNQQIPVLEKMIQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIYDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNHQDYLLLRIQDNGKGFNVDEKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLTKEEG

Nucleotide

• Length: 1035 bp

>NTDB_id=325157 EGX58_RS08690 WP_002450020.1 1728723..1729757(+) (vraS) [Staphylococcus hominis strain FDAARGOS_575]
ATGAATCACTATTTAAGAGCAATAGGATCCATGCTTATTTTAGTGTATAGCATGCTAACTGCGTTTTTATTTATAGATAA
AGTTTTTGTAAATATTATATATTTTCAAGGAATGTTCTATACTCAAATATTTGGTATACCTGTGTTTCTATTTCTTAATT
TAGTGATTATTTTACTTTGTATTATCGTTGGCTCTGTATTAGCTTATAAAATAAATCAGCAAAATGATTGGATAAAGAAT
CAAATTGAACATGCCATTGAAGGCGAAACGGTAGGGATTAATGATAAAAATATAGAACTATATAATGAGACAATTGATAT
TTATCAAATGTTAGTGCCTTTAAATCAAGAATTACAGAGATTAAGAATTAAAACTCAAAATTTAACAAATGAAAACTATA
ATATGAATGACATTAAAGTTAAAAAAATCATAGAAGATGAGCGTCAGCGTTTAGCAAGGGAACTACACGATTCAGTAAGT
CAACAACTTTTCGCAGCAAGTATGATGCTATCAGCGATAAAAGAAACAGAACTAGCACCACCTCTTAATCAACAAATTCC
AGTACTTGAGAAAATGATACAAGAATCTCAATTAGAGATGCGAGCGCTATTACTACATTTGCGACCTTTAGGACTCAAAG
ATAAATCATTAGGGGAAGGTATTAAAGATTTAGTCATTGATTTACAAAAGAAAGTACCTATGAAAGTCATTTATGATATA
CAAGATTTTAAAGTTCCTAAAGGAATTGAAGATCATCTATTTCGAATTACACAAGAGGCAATTTCAAATACATTAAGACA
TTCTAATGGAACTAAAGTGACAGTAGAATTATTTAATCATCAAGATTATTTATTATTAAGAATTCAGGATAATGGTAAAG
GTTTTAACGTAGATGAAAAAGTAGAACAAAGTTATGGATTGAAAAATATGAGAGAACGTGCATTAGAAATAGGTGCAACG
TTTCATATCGTATCTTTACCAGATTCAGGAACTAGAATAGAGGTAAAAGCACCTTTAACGAAAGAGGAGGGTTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	89.826	100	0.898