Detailed information NTG0324742

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EGV95_RS28350
• Genome accession: NZ_CP033684
• Coordinates: 5845225..5846562 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain H26027
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5840225..5851562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGV95_RS28325 (EGV95_28230)	pgeF	5840368..5841096 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
EGV95_RS28330 (EGV95_28235)	rluD	5841093..5842055 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EGV95_RS28335 (EGV95_28240)	-	5842201..5843226 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EGV95_RS28340 (EGV95_28245)	-	5843383..5843628 (+)	246	WP_009316269.1	PP0621 family protein	-
EGV95_RS28345 (EGV95_28250)	pilS	5843618..5845210 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
EGV95_RS28350 (EGV95_28255)	pilR	5845225..5846562 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EGV95_RS28355 (EGV95_28260)	thiO	5846608..5847702 (-)	1095	WP_023087807.1	glycine oxidase ThiO	-
EGV95_RS28360 (EGV95_28265)	-	5847837..5848346 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
EGV95_RS28365 (EGV95_28270)	-	5848452..5848958 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
EGV95_RS28370 (EGV95_28275)	pilV	5848949..5849506 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EGV95_RS28375 (EGV95_28280)	pilW	5849503..5850327 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EGV95_RS28380 (EGV95_28285)	pilX	5850324..5850911 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=324742 EGV95_RS28350 WP_003094694.1 5845225..5846562(+) (pilR) [Pseudomonas aeruginosa strain H26027]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=324742 EGV95_RS28350 WP_003094694.1 5845225..5846562(+) (pilR) [Pseudomonas aeruginosa strain H26027]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACTCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAAAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384