Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   EGC57_RS02295 Genome accession   NZ_CP033621
Coordinates   419346..420347 (+) Length   333 a.a.
NCBI ID   WP_002985680.1    Uniprot ID   A0A4U7H1B9
Organism   Streptococcus pyogenes strain M75     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 414346..425347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGC57_RS02270 (EGC57_02280) - 415020..415703 (-) 684 WP_023078761.1 DUF969 domain-containing protein -
  EGC57_RS02275 (EGC57_02285) - 415914..416840 (-) 927 WP_076639582.1 glycosyltransferase family 2 protein -
  EGC57_RS02280 (EGC57_02290) - 416985..417362 (-) 378 WP_076639581.1 VOC family protein -
  EGC57_RS02285 (EGC57_02295) - 417373..418038 (-) 666 WP_002985684.1 NAD(P)H-dependent oxidoreductase -
  EGC57_RS02290 (EGC57_02300) - 418087..419172 (-) 1086 WP_076639580.1 Xaa-Pro peptidase family protein -
  EGC57_RS02295 (EGC57_02305) ccpA 419346..420347 (+) 1002 WP_002985680.1 catabolite control protein A Regulator
  EGC57_RS02300 (EGC57_02310) - 420478..421476 (+) 999 WP_002985678.1 glycosyltransferase family 4 protein -
  EGC57_RS02305 (EGC57_02315) - 421478..422812 (+) 1335 WP_076639579.1 glycosyltransferase family 4 protein -
  EGC57_RS02310 (EGC57_02320) thrS 423234..425177 (+) 1944 WP_002985672.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 333 a.a.        Molecular weight: 36713.83 Da        Isoelectric Point: 5.9985

>NTDB_id=324474 EGC57_RS02295 WP_002985680.1 419346..420347(+) (ccpA) [Streptococcus pyogenes strain M75]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide


Download         Length: 1002 bp        

>NTDB_id=324474 EGC57_RS02295 WP_002985680.1 419346..420347(+) (ccpA) [Streptococcus pyogenes strain M75]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(177-332)

Bacterial regulatory proteins, lacI family (LacI)

(8-53)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7H1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus gordonii str. Challis substr. CH1

78.078

100

0.781
  ccpA Streptococcus pneumoniae D39

75.375

100

0.754
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

56.193

99.399

0.559

Multiple sequence alignment