Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FIU16_RS22625 Genome accession   NZ_CP041002
Coordinates   4379576..4380166 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain FDAARGOS_772     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4374576..4385166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FIU16_RS22610 (FIU16_22610) uhpT 4375216..4376607 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FIU16_RS22615 (FIU16_22615) uhpC 4376745..4378064 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FIU16_RS22620 (FIU16_22620) uhpB 4378074..4379576 (-) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FIU16_RS22625 (FIU16_22625) letA 4379576..4380166 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FIU16_RS22630 (FIU16_22630) ilvN 4380241..4380531 (-) 291 WP_001181713.1 acetolactate synthase small subunit -
  FIU16_RS22635 (FIU16_22635) ilvB 4380535..4382223 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  FIU16_RS22640 (FIU16_22640) ivbL 4382329..4382427 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  FIU16_RS22645 (FIU16_22645) tisB 4382992..4383081 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FIU16_RS27590 ysdE 4383344..4383418 (-) 75 WP_211180519.1 protein YsdE -
  FIU16_RS22650 (FIU16_22650) emrD 4383500..4384684 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=324112 FIU16_RS22625 WP_000633668.1 4379576..4380166(-) (letA) [Escherichia coli strain FDAARGOS_772]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=324112 FIU16_RS22625 WP_000633668.1 4379576..4380166(-) (letA) [Escherichia coli strain FDAARGOS_772]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378