Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FDP16_RS00665 Genome accession   NZ_CP040798
Coordinates   121994..123937 (+) Length   647 a.a.
NCBI ID   WP_176798197.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain CGMH058     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 116994..128937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS00645 (FDP16_00665) hexA 117413..119962 (+) 2550 WP_176798193.1 DNA mismatch repair protein MutS Machinery gene
  FDP16_RS00650 (FDP16_00670) tnpA 120156..120620 (+) 465 WP_176798194.1 IS200/IS605 family transposase -
  FDP16_RS00655 (FDP16_00675) - 120902..121372 (-) 471 WP_176798195.1 DUF3021 family protein -
  FDP16_RS00660 (FDP16_00680) brsR 121369..121809 (-) 441 WP_176798196.1 LytTR family DNA-binding domain-containing protein Regulator
  FDP16_RS00665 (FDP16_00685) hexB 121994..123937 (+) 1944 WP_176798197.1 DNA mismatch repair endonuclease MutL Machinery gene
  FDP16_RS00670 (FDP16_00690) - 123973..124494 (-) 522 WP_176798198.1 RDD family protein -
  FDP16_RS00675 (FDP16_00695) - 124478..124981 (-) 504 WP_176798199.1 helix-turn-helix domain-containing protein -
  FDP16_RS00680 (FDP16_00700) ruvA 125150..125740 (+) 591 WP_176798200.1 Holliday junction branch migration protein RuvA Machinery gene
  FDP16_RS00685 (FDP16_00705) - 125750..126322 (+) 573 WP_176798201.1 DNA-3-methyladenine glycosylase I -
  FDP16_RS00690 (FDP16_00710) - 126332..127180 (-) 849 WP_176798202.1 helix-turn-helix domain-containing protein -
  FDP16_RS00695 (FDP16_00715) - 127482..127820 (+) 339 WP_002894090.1 hypothetical protein -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73232.35 Da        Isoelectric Point: 5.0684

>NTDB_id=323256 FDP16_RS00665 WP_176798197.1 121994..123937(+) (hexB) [Streptococcus sanguinis strain CGMH058]
MSKIIELPEILANQIAAGEVIERPSSVVKELVENSIDAGASQITIEIEEAGLKSIQVTDNGEGIDHEDVPLALRRHATSK
IKKQADLFRIRTLGFRGEAIPSIASVSRFTIETATEAGQHGTLLVAQGGEIEEHEPTSSPVGTKIKIEDLFFNTPARLKY
MKSQQAELSHIVDVINRISLAYPEVAFTLISDGRELTRTAGSGNLRQAIAGIYGLATAKKMVEISASDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVINIQIDPYLADVNVHPTKQEVRISKERELMALISQ
AIATSLKEQDLIPDALENLAKSTVKRATKLEQTSLPLKENRLYYDKEQNDFFLKPQVAEQQLSFEESAKPVHEATDEKAE
PQPTSVKFAERKPASYDQLDHPELDQASLERAVDKLDQEEKSSFPELEYFGQMHGTYLFAQGKGGLYIIDQHAAQERVKY
EYYREKIGDVDNSQQQLLVPYIFEFPADNMLRIKQRMELLEDAGIFLEEYGANQFILREHPIWFKEEEIEAGIYEMCDML
LLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLLFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=323256 FDP16_RS00665 WP_176798197.1 121994..123937(+) (hexB) [Streptococcus sanguinis strain CGMH058]
ATGTCAAAAATTATCGAACTTCCAGAAATTCTAGCCAATCAGATTGCGGCCGGTGAAGTCATTGAGCGGCCTAGCAGCGT
GGTCAAGGAGCTGGTGGAAAATTCAATTGATGCGGGTGCCAGTCAGATTACTATCGAAATCGAAGAAGCTGGACTCAAGA
GCATTCAGGTGACGGATAATGGCGAGGGCATAGATCACGAAGATGTCCCTCTGGCCCTTCGACGCCATGCTACCAGCAAA
ATCAAGAAACAGGCAGATCTCTTTCGGATTCGGACACTGGGTTTCCGTGGCGAGGCCATTCCGTCCATTGCTTCTGTCTC
GCGTTTTACCATTGAAACAGCAACGGAAGCCGGCCAGCACGGGACTCTACTGGTTGCCCAAGGCGGTGAGATAGAAGAGC
ACGAGCCTACCAGCAGTCCGGTAGGAACGAAAATCAAGATAGAAGATCTCTTCTTCAATACTCCAGCCCGGCTCAAGTAT
ATGAAGAGCCAGCAGGCTGAGCTGTCCCATATCGTTGATGTGATCAATCGGATCAGTCTGGCCTATCCGGAAGTGGCTTT
CACCCTTATCAGCGACGGTCGCGAACTGACACGGACTGCCGGCAGTGGCAATCTGCGTCAGGCTATTGCGGGCATCTATG
GTCTGGCAACAGCCAAGAAAATGGTGGAAATCTCTGCTTCAGATCTGGACTTTGAGGTGAGCGGTTATGTCAGTTTGCCT
GAGCTGACTCGTGCAAATCGGAATTATATTACCATCCTCATTAATGGCCGCTACATTAAGAATTTCCTGCTCAATCGTGC
TATTTTGGATGGCTACGGCAGCAAGCTTATGGTAGGCCGCTTTCCACTAGCGGTCATCAATATCCAGATTGATCCCTATC
TGGCTGATGTCAATGTCCATCCGACCAAGCAAGAGGTGCGCATTTCTAAAGAACGCGAACTCATGGCCTTGATTTCGCAA
GCCATTGCGACCAGTCTCAAGGAGCAAGACCTTATCCCGGATGCTTTGGAAAATCTCGCCAAATCAACTGTTAAGCGTGC
GACTAAGCTTGAACAGACCAGTCTTCCACTGAAAGAAAATCGCCTCTACTACGATAAGGAGCAGAATGACTTCTTCCTCA
AGCCACAGGTGGCCGAGCAGCAGCTATCCTTTGAAGAATCAGCGAAGCCTGTTCACGAAGCGACAGATGAAAAAGCAGAA
CCGCAACCGACTTCGGTCAAATTCGCAGAGCGAAAGCCGGCCAGCTATGACCAACTAGACCATCCAGAGCTAGACCAGGC
TAGTTTGGAGCGGGCTGTAGATAAGTTGGATCAGGAAGAGAAGTCAAGCTTCCCAGAGTTAGAATATTTCGGCCAGATGC
ATGGTACCTATCTCTTTGCTCAGGGCAAGGGCGGGCTTTACATTATTGACCAACATGCTGCCCAGGAGCGGGTTAAGTAT
GAGTATTATCGGGAGAAGATTGGGGATGTGGACAATAGCCAGCAGCAGCTTTTAGTGCCCTATATCTTTGAATTTCCAGC
GGACAATATGCTGCGAATCAAGCAGCGGATGGAGCTGTTAGAAGATGCTGGCATCTTTTTAGAAGAGTATGGTGCCAACC
AGTTTATCCTCCGTGAGCATCCTATTTGGTTCAAGGAAGAGGAGATTGAAGCCGGCATCTATGAGATGTGTGATATGCTT
CTCCTGACTAAGGAAGTTTCCATCAAGAAATATCGAGCAGAGCTGGCCATTATGATGAGCTGCAAACGCTCCATCAAGGC
CAATCACAGTCTGGATGACTACTCTGCGCGTGACTTGCTCTTTCAGCTGTCCCAGTGTGACAATCCTTACAACTGCCCTC
ACGGCCGGCCGGTCTTGGTCAACTTTACCAAGTCGGATATGGAAAAAATGTTCCGCCGCATTCAGGAAAATCACACTAGC
CTACGGGAGTTAGGGAAATACTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(449-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.196

100

0.774