Detailed information NTG0323254

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FDP16_RS00645
• Genome accession: NZ_CP040798
• Coordinates: 117413..119962 (+)
• Length: 849 a.a.
• NCBI ID: WP_176798193.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain CGMH058
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 112413..124962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FDP16_RS00625 (FDP16_00645)	-	113809..114327 (+)	519	WP_176798190.1	lantibiotic ABC transporter permease	-
FDP16_RS00630 (FDP16_00650)	nrdI	114389..114877 (+)	489	WP_176798191.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
FDP16_RS00635 (FDP16_00655)	argS	114909..116597 (-)	1689	WP_176798192.1	arginine--tRNA ligase	-
FDP16_RS00640 (FDP16_00660)	argR	116898..117335 (+)	438	WP_072074757.1	arginine repressor	-
FDP16_RS00645 (FDP16_00665)	hexA	117413..119962 (+)	2550	WP_176798193.1	DNA mismatch repair protein MutS	Machinery gene
FDP16_RS00650 (FDP16_00670)	tnpA	120156..120620 (+)	465	WP_176798194.1	IS200/IS605 family transposase	-
FDP16_RS00655 (FDP16_00675)	-	120902..121372 (-)	471	WP_176798195.1	DUF3021 family protein	-
FDP16_RS00660 (FDP16_00680)	brsR	121369..121809 (-)	441	WP_176798196.1	LytTR family DNA-binding domain-containing protein	Regulator
FDP16_RS00665 (FDP16_00685)	hexB	121994..123937 (+)	1944	WP_176798197.1	DNA mismatch repair endonuclease MutL	Machinery gene
FDP16_RS00670 (FDP16_00690)	-	123973..124494 (-)	522	WP_176798198.1	RDD family protein	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 94884.37 Da
• Isoelectric Point: 5.0022

>NTDB_id=323254 FDP16_RS00645 WP_176798193.1 117413..119962(+) (hexA) [Streptococcus sanguinis strain CGMH058]
MAVEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVNAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLV
ESGYKVAIAEQMEDPKEAKGVVKREVVQVITPGTVVDSSKPDSANNFLVALDYSDGLYGLAYMDLVTGEFQVTSLEDFAL
VCGEIRNLRAREVVLGYALPEAEEQVLAGQMNLLLSYVQTALDDVQLMGEELSPMERQAAGKLLEYVRRTQMRELSHLKK
AQHYEIKDFLQMDYATKASLDLTENARSGKKHGSLYWLMDETKTAMGGRMLRSWIQRPLIDEARIIQRQNVVEVFLDHFF
ERSDLTESLKGVYDIERLASRVSFGKTNPKDLLQLAATLGNVPQIKAILQGIGSPHLARLIEGLDPIPELAGLISSAISP
DAPHVITEGNIIRTGFDETLDQYRLVLREGTGWIAELEVKERANSGISNLKIDYNKKDGYYFHVTNSQLAHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIQRLQALAQTLAAVDVLQSFAAVAEQLHLVRPVFT
AERRLQIEKGRHAVVEKVMGAQSYIPNSILLDQETDIQLITGPNMSGKSTYMRQLAIIVIMTQMGSYVPAQSASLPLFDA
IFTRIGAADDLVSGQSTFMVEMMEANRAIRQASERSLILFDELGRGTATYDGMALAQAIIEHIHHYTGAKTLFATHYHEL
TALENSLEHLENVHVATLEKDGQVTFLHKIEPGPADKSYGIHVAKIAGLPEKLLERADSILSHLESQDTGLGSELPAESR
PKRSQVAEQISLFAEGSENPVLTELRDLDIYNMTPIEVMAVVAELKKKL

Nucleotide

• Length: 2550 bp

>NTDB_id=323254 FDP16_RS00645 WP_176798193.1 117413..119962(+) (hexA) [Streptococcus sanguinis strain CGMH058]
ATGGCAGTAGAAAAGTTATCTCCAGGTATGCAGCAGTATTTGGATATCAAAAAGGACTATCCAGATGCTTTCTTGCTCTT
TCGGATGGGGGATTTCTATGAGTTGTTTTATGATGATGCGGTCAATGCCGCCCAGATTTTAGAGATTTCCTTGACCAGCC
GTAATAAAAATGCTGAAAATCCCATTCCTATGGCTGGAGTTCCCTATCATTCGGCACAGCAGTACATTGATGTTTTGGTC
GAATCAGGCTATAAGGTGGCGATTGCGGAGCAGATGGAAGATCCCAAGGAAGCCAAGGGAGTTGTTAAGCGGGAGGTCGT
TCAGGTTATCACGCCGGGAACGGTGGTGGACTCCAGTAAGCCGGACTCTGCTAATAACTTTCTGGTGGCTCTGGATTACT
CAGACGGCCTCTATGGTCTAGCTTATATGGACCTGGTGACCGGTGAGTTTCAGGTGACCAGTCTAGAGGACTTTGCCTTG
GTCTGCGGGGAAATCCGCAATTTGAGGGCTAGGGAAGTGGTGCTGGGCTATGCCTTGCCAGAAGCTGAGGAGCAGGTCTT
GGCTGGACAGATGAACCTCTTACTGTCCTATGTACAGACGGCCTTGGACGATGTTCAGCTGATGGGAGAGGAACTGTCTC
CTATGGAGCGTCAGGCAGCAGGGAAATTGCTGGAGTATGTGCGCCGGACCCAGATGAGGGAGCTCAGCCATTTGAAGAAG
GCTCAGCATTATGAAATCAAGGACTTTCTGCAAATGGATTATGCCACCAAGGCAAGTCTGGATTTGACAGAAAATGCTCG
CTCGGGCAAGAAGCACGGCAGTCTTTATTGGCTGATGGACGAGACCAAGACGGCCATGGGCGGTCGCATGCTGCGCTCTT
GGATTCAGCGTCCGCTGATTGATGAAGCGCGAATCATCCAGCGGCAGAATGTTGTCGAGGTCTTTCTGGATCATTTCTTT
GAGCGGAGTGATTTGACGGAGAGCCTCAAGGGAGTCTATGATATTGAGCGGCTGGCTAGTCGAGTGTCTTTTGGCAAGAC
CAATCCTAAAGATCTGCTGCAACTGGCGGCTACATTGGGCAATGTGCCTCAGATTAAGGCTATCCTGCAAGGAATTGGCA
GCCCGCATCTAGCTCGTTTGATTGAGGGATTGGATCCTATTCCAGAGTTGGCGGGCTTGATTAGCTCGGCCATTTCACCG
GATGCGCCCCATGTTATTACTGAGGGCAATATCATTCGGACAGGTTTTGATGAGACTTTAGATCAGTATCGGCTTGTGCT
GAGGGAGGGAACCGGATGGATTGCGGAGCTGGAAGTTAAGGAGCGTGCCAACAGCGGCATCAGCAATCTGAAGATTGATT
ACAACAAAAAAGATGGTTACTATTTCCACGTGACCAATTCCCAGCTGGCTCATGTGCCTAGCCATTTCTTCCGCAAGGCG
ACCCTGAAAAATTCGGAGCGTTTCGGAACGGAGGAGCTGGCCCGAATTGAGGGAGAGATGTTGGAGGCGCGTGAAAAATC
TGCTAATCTGGAATACGAAATTTTCATGCGGATTCGCGAGGAAGCTGGCAAATACATCCAGCGCTTGCAGGCTTTGGCAC
AAACGCTGGCAGCTGTAGATGTCCTGCAGAGCTTTGCTGCGGTGGCAGAACAACTGCATTTGGTGCGCCCTGTCTTTACT
GCGGAGCGCCGTCTGCAGATTGAAAAAGGTCGGCATGCTGTTGTGGAAAAGGTCATGGGTGCCCAAAGCTACATTCCAAA
TAGTATTCTGCTGGATCAGGAAACAGACATCCAGCTGATTACTGGGCCTAATATGAGCGGGAAATCGACTTATATGCGCC
AGCTGGCTATCATCGTTATTATGACACAGATGGGATCTTATGTGCCCGCTCAGTCTGCCAGTCTGCCGCTATTCGATGCG
ATTTTCACTCGCATCGGTGCAGCGGATGATCTGGTGTCTGGCCAGTCCACTTTTATGGTGGAAATGATGGAGGCCAATCG
GGCCATTCGGCAGGCCAGCGAGCGTTCGCTCATTCTCTTTGATGAGCTGGGTCGCGGGACGGCTACTTATGATGGGATGG
CCTTGGCTCAGGCTATTATCGAGCATATTCATCATTATACTGGGGCCAAAACCCTCTTTGCCACCCACTATCATGAGCTG
ACAGCTTTAGAGAATAGCTTGGAGCATTTGGAAAATGTCCATGTGGCAACCTTGGAAAAGGACGGACAGGTGACTTTCCT
GCATAAGATTGAGCCGGGTCCGGCTGACAAGTCTTACGGAATCCATGTGGCGAAGATTGCCGGACTTCCTGAGAAATTAC
TGGAGCGGGCAGACAGCATTTTGAGTCATTTGGAAAGTCAGGATACAGGACTAGGATCAGAGCTTCCTGCTGAATCCAGA
CCGAAGCGGTCACAAGTAGCTGAGCAGATTTCTCTTTTCGCAGAAGGGTCGGAAAATCCAGTCCTGACTGAACTCCGAGA
CTTGGACATCTACAACATGACTCCCATAGAAGTCATGGCGGTGGTAGCCGAGCTCAAGAAAAAGTTGTAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	77.503	100	0.775
mutS	Pseudomonas stutzeri strain ATCC 17587	38.74	100	0.391