Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SMI_RS08840 Genome accession   NC_013853
Coordinates   1795980..1796612 (-) Length   210 a.a.
NCBI ID   WP_000698413.1    Uniprot ID   -
Organism   Streptococcus mitis B6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1790980..1801612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS08820 (smi_1738) recD/recD2/recDB 1791513..1793879 (+) 2367 WP_000454519.1 ATP-dependent RecD-like DNA helicase Machinery gene
  SMI_RS08825 (smi_1739) tig 1794075..1795358 (-) 1284 WP_000116489.1 trigger factor -
  SMI_RS08830 (smi_1740) - 1795514..1795916 (-) 403 Protein_1713 DNA alkylation repair protein -
  SMI_RS08840 (smi_1741) vraR 1795980..1796612 (-) 633 WP_000698413.1 response regulator transcription factor Regulator
  SMI_RS08845 (smi_1742) - 1796623..1797621 (-) 999 WP_000743693.1 sensor histidine kinase -
  SMI_RS08850 (smi_1743) liaF 1797618..1798316 (-) 699 WP_001224650.1 cell wall-active antibiotics response protein LiaF -
  SMI_RS08855 (smi_1744) fni 1798393..1799403 (-) 1011 WP_000210637.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  SMI_RS08860 (smi_1745) - 1799387..1800394 (-) 1008 WP_000226748.1 phosphomevalonate kinase -
  SMI_RS08865 (smi_1746) mvaD 1800381..1801334 (-) 954 WP_000373473.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23595.19 Da        Isoelectric Point: 5.0131

>NTDB_id=32325 SMI_RS08840 WP_000698413.1 1795980..1796612(-) (vraR) [Streptococcus mitis B6]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGKLAIEQEVSKKVEYHRNHIELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=32325 SMI_RS08840 WP_000698413.1 1795980..1796612(-) (vraR) [Streptococcus mitis B6]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGGCAAACGGATCTCAAGGAATTGACTTGGCATTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTGGCCATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCGTACTTGGACAATGAAAAAATCATGCCGGTCTTGAATGCCGGTGCCAAAGGCTATATGCTCAAAACTTCAAGTGC
AGACGAACTACTCCATGCCGTCCGTAAGGTGGCTGCTGGAAAGTTGGCCATTGAGCAAGAGGTCAGCAAGAAGGTTGAAT
ACCACCGCAATCATATCGAGCTTCACGAGGACCTGACTGCGCGTGAGCGAGATGTACTTCAACTCATCGCCAAGGGTTAT
GAAAATCAGCGCATCGCAGATGAACTTTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCCAATATCCTAGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCAGCAGTCTATGCCTTTCAGCACCATTTGGTAGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

98.095

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405

Multiple sequence alignment