Detailed information NTG0323123

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EB816_RS02340
• Genome accession: NZ_CP033337
• Coordinates: 425915..426916 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY453
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 420915..431916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EB816_RS02315 (EB816_02320)	-	421591..422274 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
EB816_RS02320 (EB816_02325)	-	422483..423409 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
EB816_RS02325 (EB816_02330)	-	423554..423931 (-)	378	WP_002985686.1	VOC family protein	-
EB816_RS02330 (EB816_02335)	-	423933..424607 (-)	675	WP_023612169.1	NAD(P)H-dependent oxidoreductase	-
EB816_RS02335 (EB816_02340)	-	424656..425741 (-)	1086	WP_023612158.1	Xaa-Pro peptidase family protein	-
EB816_RS02340 (EB816_02345)	ccpA	425915..426916 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EB816_RS02345 (EB816_02350)	-	427046..428044 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EB816_RS02350 (EB816_02355)	-	428046..429380 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
EB816_RS02355 (EB816_02360)	thrS	429802..431745 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=323123 EB816_RS02340 WP_002985680.1 425915..426916(+) (ccpA) [Streptococcus pyogenes strain TSPY453]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=323123 EB816_RS02340 WP_002985680.1 425915..426916(+) (ccpA) [Streptococcus pyogenes strain TSPY453]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCCGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559