Detailed information NTG0323013

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EB818_RS02285
• Genome accession: NZ_CP033335
• Coordinates: 418158..419159 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY208
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 413158..424159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EB818_RS02260 (EB818_02270)	-	413832..414515 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
EB818_RS02265 (EB818_02275)	-	414726..415652 (-)	927	WP_076639582.1	glycosyltransferase family 2 protein	-
EB818_RS02270 (EB818_02280)	-	415797..416174 (-)	378	WP_076639581.1	VOC family protein	-
EB818_RS02275 (EB818_02285)	-	416185..416850 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
EB818_RS02280 (EB818_02290)	-	416899..417984 (-)	1086	WP_002985682.1	Xaa-Pro peptidase family protein	-
EB818_RS02285 (EB818_02295)	ccpA	418158..419159 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EB818_RS02290 (EB818_02300)	-	419290..420288 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EB818_RS02295 (EB818_02305)	-	420290..421624 (+)	1335	WP_076639579.1	glycosyltransferase family 4 protein	-
EB818_RS02300 (EB818_02310)	thrS	422046..423989 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=323013 EB818_RS02285 WP_002985680.1 418158..419159(+) (ccpA) [Streptococcus pyogenes strain TSPY208]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=323013 EB818_RS02285 WP_002985680.1 418158..419159(+) (ccpA) [Streptococcus pyogenes strain TSPY208]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559